1000 mg. 20 MINUTES. Applies only to oral form of both agents. iron sucrose, captopril. 4)Pasricha SR, Flecknoe-Brown SC, Allen KJ, Gibson PR, McMahon LP, Olynyk JK, Roger SD, Savoia HF, Tampi R, Thomson AR, Wood EM, Robinson KL. Reactions have occurred following the first dose or subsequent doses of Venofer. Monitor Closely (1)cimetidine will decrease the level or effect of iron sucrose by increasing gastric pH. Applies only to oral form of both agents. The two formulas used are presented below: Iron deficit in mg = Weight in kg x (14 Hb in g/dL) x 2.145, Volume of product required in mL = Iron deficit in mg / C in mg/mL. Comparable efficacy to that of IV iron sucrose. DOSAGE AND ADMINISTRATION: The recommended dose of Feraheme is an initial 510 mg dose followed by a second 510 mg dose 3 to 8 days later. Minor/Significance Unknown. Monitor Closely (1)dexlansoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Use Caution/Monitor. Use Caution/Monitor. Pediatric Patients: The most common adverse reactions (2%) are headache, respiratory tract viral infection, peritonitis, vomiting, pyrexia, dizziness, cough, nausea, arteriovenous fistula thrombosis, hypotension and hypertension. Volume of iron product required = 25 mL. Applies only to oral form of both agents. Hemodialysis-dependent CKD: 100 mg elemental iron IV (injection or infusion over 2-5 min) per dialysis session not to exceed total cumulative dose of 1000 mg divided in 3 doses/week. Kidney Int. Use Caution/Monitor. Avoid or Use Alternate Drug. Minor/Significance Unknown. Applies only to oral form of both agents. J Med. Initial symptoms may include hypotension, syncope, unresponsiveness, cardiac/cardiorespiratory arrest. Use Caution/Monitor. Adult Dosage and Administration: The recommended dosage of Ferrlecit for the repletion treatment of iron deficiency in hemodialysis patients is 10 mL of Ferrlecit (125 mg of elemental iron). FERAHEME Dosing & Administration - Feraheme FERAHEME has flexible dosing for your patients FERAHEME flexible scheduling gives your patients the freedom to receive the iron they need as early as 3 days apart 1 FLEXIBLE DILUTION OPTIONS 1 Dilute full contents of vial (17 mL) in 50 mL to 200 mL of: 0.9% NaCl, or 5% dextrose STORAGE 1 iron sucrose decreases levels of tetracycline by inhibition of GI absorption. Applies only to oral form of both agents. Monitor Closely (1)trientine, iron sucrose. There is in depth information below the form on the method used and on the result provided. Give each dose as 750 mg for a total cumulative dose of 1500 mg of iron per course. Minor (1)iron sucrose, benazepril. PRECAUTIONS: Before using iron sucrose, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. Calculates iron deficit for dosing iron. Applies only to oral form of both agents. iron sucrose increases levels of calcium citrate by enhancing GI absorption. Minor/Significance Unknown.iron sucrose increases levels of calcium citrate by enhancing GI absorption. Applies only to oral form of both agents. Minor/Significance Unknown. Applies only to oral form of both agents. Introduction Uses Dosage Warnings Interactions Stability Introduction Hematinic agent; a polynuclear iron (III)-hydroxide sucrose complex. Serious - Use Alternative (1)iron sucrose decreases levels of levofloxacin by inhibition of GI absorption. Applies only to oral form of both agents. When iron sucrose was administered at deliberate overdoses to rabbit dams (up to 215 mg/kg/day) marked fetal/placental iron overload was noted. The usual total treatment course of Venofer is 1000 mg. Venofer treatment may be repeated if iron deficiency reoccurs. Schweiz Med Wochenschr; 100(7):301-3. A maximum dose of 1000 mg iron can be delivered intravenously over 15 minutes, which may make it a suitable treatment for iron-deficiency anaemia outside of the hospital setting. Modify Therapy/Monitor Closely. Avoid or Use Alternate Drug. Minor (1)gymnema decreases levels of iron sucrose by inhibition of GI absorption. iron sucrose decreases levels of methyldopa by inhibition of GI absorption. Administer Venofer only intravenously by slow injection or by infusion. Separate by at least 4 hours. The recommended Feraheme dose may be readministered to patients with persistent or recurrent iron deficiency anemia. Maximum infusion rate: 100 mg / hour (Slow infusion rate of iron sucrose is recommended to minimize adverse reactions, especially hypotension) Frequency of infusion: Dose may be repeated up to 3 times weekly to provide total iron dose. Applies only to oral form of both agents. Monitor Closely (1)nizatidine will decrease the level or effect of iron sucrose by increasing gastric pH. This document does not contain all possible drug interactions. Monitor Closely (1)sodium bicarbonate will decrease the level or effect of iron sucrose by increasing gastric pH. Prior to and at regular intervals during parenteral iron therapy, evaluate serum iron, hemoglobin, and hematocrit. Applies only to oral form of both agents. LBW = Lean body weight in kg. 2.1 . Schweiz Med Wochenschr; 100(7):301-3. Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. Separate dosing of tetracyclines from these products. Monitor Closely (1)iron sucrose decreases levels of liothyronine by inhibition of GI absorption. Then you can click on the Print button to open a PDF in a separate window with the inputs and results. 1998 Feb;25(1):65-8. iron sucrose increases levels of calcium chloride by enhancing GI absorption. Administer on 5 different occasions over a 14 day period. Use Caution/Monitor. If hypersensitivity reactions or signs of intolerance occur during administration, stop Venofer immediately. Applies only to oral form of both agents. Venofer is manufactured under license from Vifor (International) Inc., Switzerland. 4) Gozzard D. (2011) When is high-dose intravenous iron repletion needed? When administered via infusion, dilute up to 750 mg of iron in no more than 250 mL of sterile 0.9% sodium chloride injection, USP, such that the concentration of the infusion is not less than 2 mg of iron per mL and administer over at least 15 minutes. Diagnosis and management of iron deficiency anaemia: a clinical update. an automated flowchart approach. Modify Therapy/Monitor Closely. Injection site discoloration has been reported following extravasation. 1995 Mar-Apr;11(2):163-8. Minor (2)calcium gluconate decreases levels of iron sucrose by inhibition of GI absorption. iron sucrose decreases levels of ciprofloxacin by inhibition of GI absorption. The dosage of Venofer is expressed in mg of elemental iron. By entering this website, you acknowledge that you are a licensed healthcare professional practicing in the United States. Applies only to oral form of both agents. Applies only to oral form of both agents. Treatment of anemia due to iron deficiency. After total replacement dose completed, need for ongoing IV doses should be re-assessed monthly. Pain, swelling, or redness at the injection site may occur. https://www.uptodate.com/ (Requires subscription). Applies only to oral form of both agents. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=abacb7fa-2fc2-471e-9200-944eeac8ca2a. Minor/Significance Unknown. Venofer treatment may be repeated if necessary. Venofer and the Venofer logo are registered trademarks of Vifor (International) Inc., Switzerland. This website also contains material copyrighted by 3rd parties. Venofer® (iron sucrose) injection, USP is indicated for the treatment of iron deficiency anemia (IDA) in patients with chronic kidney disease (CKD). Use Caution/Monitor. Use Caution/Monitor. 3) Bayraktar UD, Bayraktar S. (2010) Treatment of iron deficiency anemia associated with gastrointestinal tract diseases. in the colostrum of 10 iron deficient breastfeeding women who were 2 to 3 days postpartum and received a single dose of 100 mg of intravenous iron . Fulminant symptoms may include general paleness, confusion or episodes of passing out. Copyright 1993-2021 If we don't have the calculator you need we'll try to make it for you and add it to the website. Serious hypersensitivity reactions, including anaphylactic-type reactions, some of which have been life-threatening and fatal, have been reported in patients receiving Venofer. 2.1 Dosage - Total dose infusion The dose calculation for CosmoFer is based on patients body weight according to the table below and is diluted in 500mLs of normal saline. Applies only to oral form of both agents. Assessing new treatment options. iron sucrose decreases levels of penicillamine by inhibition of GI absorption. Applies only to oral form of both agents. If no signs or symptoms of anaphylactic-type reactions follow the test dose, administer the full therapeutic INFeD dose. Applies only to oral form of both agents. Follow your doctor's directions carefully.Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft).A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. Applies only to oral form of both agents. Transferrin saturation (TSAT) values increase rapidly after intravenous administration of iron sucrose; do not perform serum iron measurements for at least 48 hours after intravenous dosing. Minor/Significance Unknown.iron sucrose increases levels of calcium acetate by enhancing GI absorption. Copyright 2021 GlobalRPH - Web Development by, Calculation of the Total Iron Deficit Alternative equation. Administer iron products at least 2 hr before and no less than 6 hr after each dose to avoid chelation with magnesium. Modify Therapy/Monitor Closely. IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. Anemia of chronic disease (ACD), Calculation of the Total Iron Deficit equation appears in Cosmofer PI, Iron Dextran Dosing Calculator (iron deficit). lansoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Minor/Significance Unknown. All Rights Reserved. Use Caution/Monitor. Administer iron products at least 2 hr before and no less than 6 hr after each dose to avoid chelation with magnesium. Fatal reactions have also occurred in situations where the test dose was tolerated. Adults and Children over 15 kg (33 lbs): Dose (mL) = 0.0442 (Desired Hb - Observed Hb) x LBW + (0.26 x LBW), Desired Hb = the target Hb in g/dl. David McAuley, Pharm.D. Monitor Closely (1)esomeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Venofer is indicated for the treatment of iron deficiency anemia (IDA) in patients with chronic kidney disease (CKD). Monitor Closely (1)iron sucrose will decrease the level or effect of sarecycline by inhibition of GI absorption. Applies only to oral form of both agents. Applies only to oral form of both agents. Pasricha SR, Flecknoe-Brown SC, Allen KJ, Gibson PR, McMahon LP, Olynyk JK, Roger SD, Savoia HF, Tampi R, Thomson AR, Wood EM, Robinson KL. Drug: Comments: A: Acyclovir 1: Dose using a 40% adjusted body weight; Amikacin 2: Dose using a 40% adjusted body weight; Amphotericin B (liposomal) 3 Consider capping body weight to 100 kg; Atracurium 4: Dose using ideal body weight; The use of ideal body weight has been shown to be associated with a more predictable muscle strength recovery within 60 minutes and a lack of need for antagonism . Most The usual adult total treatment course of Venofer is 1000 mg. Venofer treatment may be repeated if iron deficiency reoccurs. Minor/Significance Unknown. Monitor Closely (1)iron sucrose decreases levels of penicillamine by inhibition of GI absorption. calcium chloride decreases levels of iron sucrose by inhibition of GI absorption. Administer a test INFeD dose prior to the first therapeutic dose. The weight of the patient is taken into account in order to estimate iron stores, while haemoglobin is required as both current measured and target. IDA symptoms are often nonspecific and include tiredness, weakness, shortness of breath. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. This drug is available at a higher level co-pay. Interaction only with oral iron administration. Use Caution/Monitor. Slow or stop the infusion if adverse reactions occur. Applies only to oral form of both agents. 2) Koch TA, Myers J, Goodnough LT. (2015) Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations. Applies only to oral form of both agents. Divide the calculated dose by the patient's weight (IBW if BMI >30, or actual body weight (ABW) if BMI30) to ensure it does NOT exceed 20mg/kg. . If you have private insurance, Venofer or Monoferric may be on the list of covered medications. Taking the case of a patient weighing 75 kg (165.3 lbs) with a target hemoglobin value of 13 g/dL (130 g/L or 8.07 mmol/L), an actual hemoglobin of 9.5 g/dL (95 g/L or 5.9 mmol/L) and iron stores of 500 mg, the iron deficit is: Iron deficit = 75 x (13 9.5) x 2.4 + 500 = 1,130 mg. Deferoxamine chelates iron. Fill in the calculator/tool with your values and/or your answer choices and press Calculate. Hemodialysis-dependent: 0.5 mg/kg IV q2weeks for 12 weeks; not to exceed 100 mg/dose, Non-dialysis dependent or peritoneal-dependent (on erythropoietin): 0.5 mg/kg IV q4weeks for 12 weeks; not to exceed 100 mg/dose, sodium sulfate/?magnesium sulfate/potassium chloride, sodium sulfate/potassium sulfate/magnesium sulfate, Serious hypersensitivity reactions reported, including anaphylactic-type reactions, some of which have been life-threatening and fatal, Patients may present with shock, clinically significant hypotension, loss of consciousness, and/or collapse, If hypersensitivity reactions or signs of intolerance occur during administration, stop infusion immediately, Monitor patients for signs and symptoms of hypersensitivity during and after administration for at least 30 minutes and until clinically stable following completion of the infusion, Animal reproduction studies of iron sucrose administered to rats and rabbits during period of organogenesis at elemental iron doses equivalent to maximum recommended human dose based on body surface area revealed no evidence of harm to the fetus; adverse outcomes in pregnancy occur regardless of health of mother or use of medications, Iron deficiency anemia during pregnancy should be treated; untreated IDA in pregnancy is associated with adverse maternal outcomes such as post-partum anemia; adverse pregnancy outcomes associated with IDA include increased risk for preterm delivery and low birth weight, HD-dependent and non-dialysis-dependent CKD: Dilute with up to 100 mL of 0.9% NaCl, PD-dependent CKD: Dilute with up to 250 mL of 0.9% NaCl, Undiluted: Administer by slow IV injection over 2-5 min, Diluted solutions: Administer IV over 15 min, Undiluted: Administer by slow IV injection over 5 minutes, Diluted solutions: Administer IV over 5-60 minutes, Store in original carton at 20-25C (68-77 F); excursions permitted to 15- 30C (59-86F), Syringe: Store at room temperature (25C) or under refrigeration (4C) for up to 7 days, IV infusion: Store at room temperature (25C) for up to 7 days. 4. rabeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Applies only to oral form of both agents. Evaluate the hematologic response (hemoglobin, ferritin, iron and transferrin saturation) at least one month following the second Feraheme infusion. Hemoglobin can be input in g/dL, g/L or mmol/L and refers to the amount of hemoglobin in the red blood cells. Use Caution/Monitor. 1996 Aug;11(4):139-46. Avoid or Use Alternate Drug. No additional iron to replenish stores. iron sucrose decreases levels of moxifloxacin by inhibition of GI absorption. The elemental iron product used is Iron sucrose 20 mg/mL. Applies only to oral form of both agents. Can't find what you need? Applies only to oral form of both agents. The dosing for iron replacement treatment in pediatric patients with HDD-CKD has not been established. The cost of Venofer is $145 for a dose of 300 mg and Monoferric is $274 for a dose of 500mg. J Lab Clin Med. World J Gastroenterol; 16(22): 27202725. Ganzoni AM. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. Iron Deficiency Anemia: Periodic hematologic determination (hemoglobin and hematocrit) is a simple and accurate technique for monitoring hematological response, and should be used as a guide in therapy. Serious - Use Alternative (1)iron sucrose decreases levels of gemifloxacin by inhibition of GI absorption. commonly, these are "non-preferred" brand drugs or specialty Due Date form Ultrasound Report. Calculosaurus | Medical calculators for obstetrics and gynaecology Use the menu to browse through our clinical calculators. Am J Hosp Pharm. Do not dilute to concentrations below 1 mg/mL [see How Supplied/Storage and Handling [16.2].) Iron deficiency anemia calculator (diagnosis), Iron deficiency anemia vs. 5. IMPORTANT SAFETY INFORMATION DOSAGE AND ADMINISTRATION Pediatric Patients (2 Years of Age and Older) Diluted with 0.9% Sodium Chloride Injection at concentrations of 1 to 2 mg/mL, 2 doses of 300 mg/250 mL over 1.5 hrsplus1 dose of 400 mg/250 mL over 2.5 hrs. Iron stores are input as default 500 mg on the assumption that the patient weight is greater or equal to 35 kg (77 lbs). ibuprofen/famotidine will decrease the level or effect of iron sucrose by increasing gastric pH. In most cases, adult patients require a cumulative dose of elemental iron of at least 1 g. Most commonly, iron replenishment therapy is done intravenously: As total dose (iron-dextran or iron carboxymaltose); Iron deficiency is common during childhood growth, prolonged periods of sickness, in convalescence or during pregnancy. Have resuscitation equipment and personnel trained in the detection and treatment of anaphylactic-type reactions readily available during INFeD administration. INDICATIONS AND USAGE: Intravenous or intramuscular injections of INFeD are indicated for treatment of patients with documented iron deficiency in whom oral administration is unsatisfactory or impossible. There is limited experience with administration of an infusion of 500 mg of Venofer, diluted in a maximum of 250 mL of 0.9% NaCl, over a period of 3.5 to 4 hours on Day 1 and Day 14. Applies only to oral form of both agents. Adding plans allows you to compare formulary status to other drugs in the same class. Applies only to oral form of both agents. The dosage of Venofer is expressed in mg of elemental iron. INFED- iron dextran injection [Package insert], Hemoglobin iron deficit (mg) = weight (kg) x (14 - Hgb) x (2.145) Note: Hbg (current hemoglobin level) units: (g/dL) Alternatively: Volume of product required (mL) = [weight (kg) x (14 - Hgb) x (2.145)] / C Where C= concentration of elemental iron (mg/ml) in the product being used: Iron dextran: 50 mg/mL. Hypotension following administration of Venofer may be related to rate of administration and/or total dose delivered. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. Monitor Closely (1)omeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Where: Medicine concentration Amount of active substance per a given volume of your drug. Available for Android and iOS devices. Serious - Use Alternative (1)iron sucrose decreases levels of ciprofloxacin by inhibition of GI absorption. Steps on how to print your input & results: 1. Use Caution/Monitor. iron sucrose decreases levels of minocycline by inhibition of GI absorption. Drug Des Devel Ther; 5: 5160. Adverse pregnancy outcomes associated with IDA include increased risk for preterm delivery and low birth weight. Use Caution/Monitor. For patients receiving hemodialysis, administer Feraheme once the blood pressure is stable and the patient has completed at least one hour of hemodialysis. 2 DOSAGE & ADMINISTRATION Venofer must only be administered intravenously either by slow injection or by infusion. If these effects continue or worsen, tell your doctor.Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. These can be input in g/dL, g/L or mmol/L. Use Caution/Monitor. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvdmVub2Zlci1pcm9uLXN1Y3Jvc2UtMzQyMTYy, View explanations for tiers and Applies only to oral form of both agents. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. It varies from increases in dietary intake of iron (usually for prophylaxis purposes) to oral, intramuscular or intravenous therapy. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The dose of Venofer must be individually calculated for each patient according to the total iron deficit calculated with the following Ganzoni formula, for example: Total iron deficit [mg] = BW [kg] x (target Hb - actual Hb) [g/dl] x 2.4* + storage iron [mg] Below 35 kg BW: 35 kg BW and above: Target Hb = 13 g/dl and storage iron = 15 mg/kg BW Give each dose as 750 mg for a total cumulative dose not to exceed 1500 mg of iron per course. STORAGE: Consult the product instructions and your pharmacist for storage details. Coadministration of ciprofloxacin with multivalent cation-containing products may reduce the bioavailability of ciprofloxacin by 90%. Ferric gluconate: 12.5 mg/mL Schrier SL, Mentzer WC, Landaw SA. Use Caution/Monitor. Monitor Closely (1)iron sucrose decreases levels of thyroid desiccated by inhibition of GI absorption. Venofer [package insert]. Intravenous Injection - PRIOR TO THE FIRST INTRAVENOUS INFeD THERAPEUTIC DOSE, ADMINISTER AN INTRAVENOUS TEST DOSE OF 0.5 ML. Results: Twelve children (6 females) aged 1.2-14 years (median age 8.9 years) received at least one dose of . Your body may also need more iron if you use the drug erythropoietin to help make new red blood cells.Iron is an important part of your red blood cells and is needed to transport oxygen in the body. 3. SIDE EFFECTS: Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. Although anaphylactic reactions known to occur following INFeD administration are usually evident within a few minutes, or sooner, it is recommended that a period of an hour or longer elapse before the remainder of the initial therapeutic dose is given. Copyright 2014 - 2023 The Calculator .CO |All Rights Reserved|Terms and Conditions of Use, Intravenous iron-dextran: therapeutic and experimental possibilities, Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations, Treatment of iron deficiency anemia associated with gastrointestinal tract diseases, Diagnosis and management of iron deficiency anaemia: a clinical update. There is no resource limitation, as if the tool was hosted on your site, so all your users can make use of it 24/7; The necessary tool updates will take place in real time with no effort on your end; A single click install to embed it into your pages, whenever you need to use it. Administer iron products at least 2 hr before and no less than 6 hr after each dose to avoid chelation with magnesium. Alternatively the total dose may be calculated: Dose (mL) = 0.0442 (Desired Hb - Observed Hb) x LBW + (0.26 x LBW) Based on: Desired Hb = the target Hb in g/dl. Am J Kid Dis 2001; 38 988991. The primary endpoint was the proportion of patients with . Use Caution/Monitor. The dosage of Venofer is expressed in mg of elemental iron. Allow at least 30 minutes between administration of Feraheme and administration of other medications that could potentially cause serious hypersensitivity reactions and/or hypotension, such as chemotherapeutic agents or monoclonal antibodies. Applies only to oral form of both agents. The plasma ferritin level as a reliable index of body iron stores following intravenous iron dextran. In post-marketing safety studies of Venofer in 1,051 patients with HDD-CKD, adverse reactions reported by >1% were cardiac failure congestive, sepsis and dysgeusia. Administer ciprofloxacin at least 2 hours before or 6 hours after using these products. Human studies not conducted. Patients diagnosed with iron deficiency are prescribed iron supplementation, either to replete body stores or to correct anemia. Patients with a history of drug allergy or multiple drug allergies may be at increased risk of anaphylactic-type reactions to INFeD. Administer Venofer in 3 divided doses, given by slow intravenous infusion, within a 28 day period: 2 infusions each of 300 mg over 1.5 hours 14 days apart followed by one 400 mg infusion over 2.5 hours 14 days later. -Hgb deficit (grams) = Hgb deficit (g/dL) x blood volume (dL) -Iron deficit (mg) = Hgb deficit (grams) x 3.3 (mg Fe/g Hgb) [Note: 3.3 x 0.65 = 2.145] Otherwise, call a poison control center right away. Formula for calculating the required dose of iron sucrose 1. Drug class: Iron products. In key trials, ferric carboxymaltose increased Hb levels and replenished iron stores as effectively as IV iron sucrose . calcium acetate decreases levels of iron sucrose by inhibition of GI absorption. You can further save the PDF or print it. Share cases and questions with Physicians on Medscape consult. May increase risk of hypotension. 2. Avoid or Use Alternate Drug. Then enter the value of the Dosage and choose the unit of measurement from the drop-down menu. USES: This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. A patients lean body weight (or actual body weight if less than lean body weight) should be utilized when determining dosage. 1. Applies only to oral form of both agents. The therapeutic management of IDA focuses on the replenishment of the iron stores through methods that have been mentioned above. March 2, 2015 [IRON SUCROSE REQUIREMENT CALCULATION FOR SEVERE ANEMIA] DPMU Anantapuramu | National Health Mission 1 Formula for calculating the required dose of Iron sucrose 2.4 X Pre-pregnancy Weight in Kgs X Hb% deficit{11-actual Hb%} in mgs Plus Iron required to replenish the iron stores = 500mg Prepregnancy Weight = 45 kgs . Kumpf VJ, Holland EG. Use (s): Iron deficiency anemia in patients with chronic kidney disease (CKD) Iron Deficiency In Pregnancy Calculator, Mean Corpuscular Hemoglobin Concentration (MCHC) Calculator. Found in multiple references. Auerbach M, Witt D, Toler W, Fierstein M, Lerner RG, Ballard H. Clinical use of the total dose intravenous infusion of iron dextran. Crown Rump Length and Nuchal Translucency. Applies only to oral form of both agents. Avoid or Use Alternate Drug. All Rights Reserved. Use Caution/Monitor. Iron deficiency anemia is the type of anemia caused by iron depletion. DOSAGE AND ADMINISTRATION: Oral iron should be discontinued prior to administration of INFeD. Monitor Closely (1)sodium sulfate/?magnesium sulfate/potassium chloride decreases levels of iron sucrose by inhibition of GI absorption. Serious - Use Alternative (1)iron sucrose decreases levels of oxytetracycline by inhibition of GI absorption. Iron sucrose (Venofer) 100 mg/5 mL vial 200 - 300 mg given every 3-7 days 300 mg doses are given over 90 minutes 500 mg/dose. Applies only to oral form of both agents. Before using, check this product visually for particles or discoloration. famotidine will decrease the level or effect of iron sucrose by increasing gastric pH. Hemoglobin iron deficit = 60 x (14 - 8) x (2.145) = 772 mg iron. Consult your doctor before breast-feeding. Observed Hb = the patients current hemoglobin in g/dl. Anemia of chronic disease (ACD), Calculation of the Total Iron Deficit equation appears in Cosmofer PI, Calculation of the Total Iron Deficit Alternative equation, Iron Dextran Dosing Calculator (iron deficit), HONcode standard for trust- worthy health, Pediatric Oncology: Diagnosis And Prognosis Communication, Pharmacosmos A/S, CosmoFer low molecular weight (Mw) iron dextran. Immune system disorders: Anaphylactic-type reactions, angioedema, Nervous system disorders: Convulsions, collapse, light-headedness, loss-of-consciousness, Respiratory, thoracic and mediastinal disorders: Bronchospasm, dyspnea, Musculoskeletal and connective tissue disorders: Back pain, swelling of the joints, General disorders and administration site conditions: Hyperhidrosis, Published studies on intravenous iron sucrose treatment after first trimester of pregnancy not shown adverse maternal or fetal outcomes; available reports of intravenous iron sucrose use in pregnant women during first trimester are insufficient to assess risk of major birth defects and miscarriage; iron deficiency anemia during pregnancy should be treated because there are risks to mother and fetus associated with untreated iron deficiency anemia (IDA) in pregnancy; risks to fetus associated with maternal severe hypersensitivity reactions, Severe adverse reactions including circulatory failure (severe hypotension, shock including in the context of anaphylactic reaction) may occur in pregnant women with parenteral iron products which may cause fetal bradycardia, especially during second and third trimester, Iron sucrose is present in human milk, and available published reports following exposure to 100-300 mg intravenous iron sucrose have not reported adverse reactions in breastfed infants; there are no data on effects on milk production, Developmental and health benefits of breastfeeding should be considered, along with mothers clinical need for treatment and any potential adverse effects on breastfed child from therapy or from underlying maternal condition.
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