does david sinclair eat fruit

David has described his yogurt making process as so: David has specifically mentioned Bravo as the brand of yogurt culture he uses, for example at 1:12:28 of his interview on the Ben Greenfield podcast. The NR Chromadex sell has a patent on it, which reduces competition. However, when we look at the company hes invested in, Longevity Labs, whos first product is a spermidine supplement under the brand SpermidineLIFE. Its really changed my life; I have more energy-its great., RELATED READING: Dr. Andrew Hubermans Supplement List, Cold weather increases your immune system, says Dr. Sinclair, who recommends people get their hands on a cold thermometer and put it in their armpits when they wake up-the colder the reading in 10 minutes, the healthier you are. Dr. Sinclairs work on aging has profoundly impacted our understanding of how aging works and what it means to be old- and, more importantly, how we can live longer, healthier lives without radical life extension technologies. This means that it cannot work. Dried fruit essentially concentrates the calories and sugar into smaller packets, making it easier to consume excess calories. However, there isnt yet research on optimal dosage for someone with already healthy blood glucose levels. Resveratrol is thought to act as a caloric restriction mimetic, which activates beneficial cellular pathways. (2010). You can pick up his book Lifespan: Why We Age and Why We Dont Have To on Amazon. Thats a wordy quote from the paper, but in essence, they were testing a micronized resveratrol formulation against a non-micronized version. We're proud to have him on our team as the Chairman of the InsideTracker Scientific Advisory Board. The secret, Sinclair says, is something he calls "health span." Hear about the latest developments in aging research, lifestyle practices for longevity, exercise and nutrition science, and more. David clarified on the recent podcast with Rhonda Patrick that the NMN doesnt need to be taken with a fat source he specifically mentions taking his NMN in capsules, downed with a glass of water in the morning. (David Sinclair, the Harvard scientist who discovered resveratrol, eventually sold his company for 750 million dollars.) In the longevity circles, he is known for supporting resveratrol (one of the compounds found in red wine) as a supplement to slow the aging process. Quercetin Quercetin is a flavonoid contained in many fruits and vegetables like grapes, apples, broccoli, and tomatoes. Weve gotten rid of the idea that its just genes against destiny-we know that we can change the genes, and we can change our destiny., RELATED READING: Tim Ferriss Supplement Stack. Currently the evidence around spermidine and longevity appears in its infancy. Below we'll start by looking in detail on each of the supplements that David Sinclair takes. When you intermittent fast, you can reduce insulin levels by 40 percent, and that helps improve health in many different ways., RELATED READING: Tim Ferrisss 3-Day Fasting Protocol, Dr. Sinclair believes that people should use natural supplements instead of prescription drugs because theyre less expensive and more effective. Sinclair doesn't go into great detail about what to eat, but does touch on some key points: Eat less meat, eat more plants. Given that his focus is on tackling aging and he appears to exemplify this work its natural to ask whats his secret? Know your aging rate. Lifespan: Why We Ageand Why We Don't Have To. Please consult a healthcare practitioner before making changes to your diet or taking supplements that may interfere with medications. Dr. Sinclair emphasizes that you cant take shortcuts when it comes to planning a diet and exercise regimen-the best way to prolong life expectancy is to eat st healthy balanced diet food, taking care not to overload your body with fructose or simple sugars. Examples of generally reputable brands include: Whilst David generally tries to get all the vitamins and minerals he needs from his diet, he does still take some vitamins daily. David uses a blood testing service called Inside Tracker to track his biomarkers. (2019). Use cold/hot therapy. In the book he goes in great detail on how we can slow down, or even reverse, aging. Examples of brands for vitamin K2 include: David mentions on Twitter (link) taking his daily Omega 3-6-9. This could lead to increased cardiovascular risk as a result23Circulating uncarboxylated matrix Gla protein, a marker of vitamin K status, as a risk factor of cardiovascular disease van den Heuvel et al. For example with curcumin, whose absorption can be improved through micronization (for example Theracurmin). Molecules that are discovered today will need years of testing before they can even come close to rival the amount of data and patient years accumulated by metformin. Based on multiple, recent interviews and his book, Dr. Sinclair's supplement and longevity drug stack likely looks as follows: Nicotinamide mononucleotide (NMN ): 1g per day, in the morning Resveratrol: 1g per day, in the morning Metformin: 800 mg, in the evening Vitamin D3: ideally 4,000 to 5,000 IU per day No specific details are available at the moment. (2019). Its worth noting the study used NR, not NMN. David mentions in his interview with Rhonda Patrick a few nuances around the storage of resveratrol: David takes his resveratrol in the morning, mixed into a spoon of homemade yogurt (using the Bravo starter culture), in order to increase its bio-availability. Theres little to no doubt in the research community that we need to restore NAD function; but the jury is still out on what the best method will be. Any statements made on this website have not been evaluated by the FDA and any information or products discussed are not intended to diagnose, cure, treat or prevent any disease or illness. . High protein intake is associated with low plasma NAD+ levels in a healthy human cohort . So where does the vitamin K2 supplementation come in? Dr. David Sinclair is a world-renowned longevity scientist best known for his research on resveratrol and the sirtuin genes of yeast. In summary, current evidence for this issue is lacking, and as far as I can tell, David Sinclair is no longer taking any supplements to tackle potential methyl group depletion. When David visited his family, they let him into a secret Denham had been taking alpha lipoic acid for most of his life, primarily thinking it was an antioxidant. However, if youre interested to make your own version expand the box below to learn more. Looking at the data online around stabilized NR, I found: What I gather from that, is that NR in its chloride form is stabilized. Vitamin K1 is the most abundant in a western diet, primarily found in leafy green vegetables. We also recommend resveratrol in powder form by Renue by Science so you can . However, he doesnt fully subscribe to the belief that calorie restriction can dramatically prolong human longevity. Read and learn about hide. Resveratrol is light sensitive, and when left exposed to light it turns brown. Initially (circa 2019) David mentioned taking a supplement called betaine, also known as trimethylglycine. So a 10 mg serving of spermidine trihydrochloride will contain approximately 5 mg of pure spermidine. You can probably extend the life of mice by doing wheel running, but its not for another ten years-its maybe 5 percent longer., Dr. Sinclair should know, he conducted many of the first studies showing the health benefits of caloric restriction in yeast and its effects on human cells growing in lab dishes; later, these experiments led to clinical trials in humans. He also confirms that Polygonum cuspidatum (Japanese Knotweed) is a good source for the resveratrol. He explains that this small daily dose may reduce inflammation, leading to reduced risks of chronic disease in the long run. Whilst the shelf life of resveratrol can be extended by avoiding excessive heat. Depending on how tightly you fill them you may be a marginally over or under 1g, but it wont be by much. Examples of alpha lipoic acid brands are: Also in the podcast with Dave Asprey (link), David says that he takes Coenzyme Q10 because hes taking a statin. He goes on to say that he takes it daily, and uses the S form, rather than the R form; R-Lipoic Acid. We looked at what he does to stay youthful, and what supplements David Sinclair takes. Food Addiction: Why We Can't Stop Eating - Dr. Alan Goldhamer Dr. Alan Goldhamer - The Crazy Benefits of Water Fasting and Living a Plant-Based SOS-Free Lifestyle. They found a noticeable benefit in the subjects with cognitive impairment which is great news for those in that demographic. If you're chomping at the bit to implement Sinclair's tips into your life, then we recommend you keep reading. So consumption with yogurt (or another fat source) is important. He has probably received 0 hours of nutritional education, but also does not claim to be even remotely an expert on nutrition. Concluding with mention of the blood testing he uses to monitor his health and ensure his supplement interventions are working. Cold is the future-we evolved as cold-weather animals., Dr. Sinclair believes that your genetic make-up is not a predictor of your future health. Amongst Chromadexs scientific advisors is Charles Brenner, who first discovered NR, and showed it could extend the life of yeast cells. Senolytic molecules have the ability to kill off senescent cells. You might have heard about Dr. David Sinclair on the Joe Rogan Experienceand you are now curious about what does he eat and what supplements he does take. Each group consisted of ten male participants and two female participants. Theres an evolutionary theory that the reason we like the heat is that it simulates our African origins, where everything was hot and tropical, says Dr. Sinclair. Calorie restriction, can reverse the decline of NAD+. In human experiments, after fasting overnight, people get about half their energy from burning sugar and half from burning fat. He holds a PhD from the University of New South Wales (Sydney, Australia) and is a Full Professor at Harvard where is working since 1999. He notes in a blog post on NMN & NR that: The main seller of Nicotinamide Riboside is Chromadex, who sell Niagen (pictured above). He frequently uses a sauna in conjunction with a cold bath. He takes a couple of Bravo yogurt starter culture sachets, Combines them with whole milk in a mason jar, Puts the jar in the oven over night on a low heat (~95F), Next morning he takes it out, and its ready to be chilled and eaten. Consider eating only one to two meals per day, exercising at a low intensity, and reducing or eliminating alcohol and meat to improve longevity. In an effort to increase absorption across the gastro-intestinal tract and thus systemically available parent compound, there has been considerable interest in the pharmaceutical manipulation of resveratrol. However, on the latest interview with Joe Rogan, they discussed a 2018 paper which showed metformin inhibits mitochondrial adaptations to aerobic exercise training. Nevertheless, he limits his red meat consumption because it contains Trimethylamine N-oxide which is associated with an increased risk of heart disease. This was all in an abundance of caution, rather than due to any new research that backed up the risk of methyl depletion. Dr Sinclair appeared on the cover of the Time Magazine's 100 most influential people in the . David takes it on an empty stomach in the morning, so mixes it with a bit of home made yogurt. Rhonda Patrick's General Eating Guidelines Rhonda Patrick's Breakfast Breakfast 1 Eggs Tomatillo Salsa Avocado Oil Mustard Powder Kale Grapefruit Breakfast 2 Cereal Blueberries Pomegranate Flaxseed Coconut Milk Raw Cacao Nibs Hydrolized Collagen Powder Almond Butter Yogurt or VSL #3 Rhonda Patrick on Coffee and Intermittent Fasting Like Attia, Sinclair has his own checkered history of promoting wildly unsupported hypotheses. Yes, David Sinclair is legit. It is also possible to buy spermidine in a pure form. You really want to avoid moisture (water) mixing with the resveratrol, as this will rapidly decrease its shelf life. This is viable for David who exercises vigorously in the order of 1-2x per week, but for someone training often, this might be impractical. Not to be confused alpha linolenic acid (ALA) which is a source of omega-3 fatty acids, often found in seeds. There has been some concern in the field that consuming NR or NMN could decrease the bodys methyl groups and lead to health problems. Dr. David Sinclair is an acclaimed Harvard professor doing some of the world's most groundbreaking works on human longevity. After the milk has reached 180F you can then cool it down to around 115F (a milk thermometer makes this much easier; either. In 2008, he sold his company Sirtris, which was developing resveratrol, for $720 million to Glaxo-Smith-Kline. You can search the ~290 comments using the search box at the top of the comments. Interestingly, when older mice were fed NMN, they had the same NAD+ levels of younger mice. Though Dr. David A. Sinclair has received numerous awards, he still works hard towards achieving more scientific breakthroughs and gives lectures to promote awareness about nutrition and dietetics. Vitamin K is an essential micronutrient thats plays a crucial role in the ability to form blood clots, and to transport calcium around the body. Dr. His balanced meals contain eating many veggies and fruit daily, while he is not eating meat. Alternatives to the oven are 1) Wrap your container in a blanket and place it in a warm part of your house. showed that 250mg of NMN daily in 65+year old men raised their NAD levels and improved their muscle strength. Expand the section below to see a list of food products high in spermidine content: Beyond this list, theres spermidine in many more different foods. Using these products for healthspan and lifespan benefits is new territory and needs further research. The professor's name is David Sinclair, award-winning scientist and author of the new book Lifespan: . Let's be clear: This isn't a clinical trial and the answer is NOT one molecule. I limit calories greatly, but I do exercise every day, he says., RELATED READING: Dr. Peter Attias Supplement List, Biohacking Toolkit, & Diet, We all have a certain percentage of fat in our body, and we also have some sugar thats stored in the liver. (00:21:17) Daily Step Count and Walking After Eating (00:22:33 . Its quite likely that David didnt talk about Coenzyme Q10 in his book because its specific to him and his use of a statin. Per Sinclair: "Almost any periodic fasting diet that does not result in malnutrition is likely to put your longevity genes to work in ways that will result in a longer, healthier life." Diet: Eat Healthy. Sinclair explains that your liver will start making glucose at a steady level after a few weeks, so there won't be large spikes of insulin that put you in a glucose deficit and make you tired. What does David think of Nicotinamide Riboside (NR)? Therefore, the aim of this clinical study was to investigate whether consumption of SRT501, a micronized resveratrol formulation designed by Sirtris, a GSK Company is safe and generates measurable and pharmacologically active levels of parent agent in the circulation and in the liver. He exercises in order to stay healthy and mentally sharp, rather than to be muscular, He doesnt smoke, avoids microwaved plastic, excessive sun exposure, X-rays, and CT scans, Aims to keep his BMI in the optimal range for healthspan, which for him he says is 23 to 25, Tries to stay on the cool side during the day, and at night when sleeping, Reduced inflammation and oxidative stress in healthy people, Improvements in memory tasks for obese, but otherwise healthy 50-75 year olds, Improvements in metabolic and cardiovascular markers, in people with obesity. If you have found Dr. David Sinclair' tips valuable, you will just devour his book: "Lifespan: Why We Ageand Why We Don't Have To". The goal of this blog is to share information around health and longevity, with the hope that others find it useful. 500mg of quercetin daily in the morning with yogurt. Any questions or comments, please leave them below. David Sinclair ( @davidasinclair) is a Professor in the Department of Genetics at Harvard Medical School Check out his professor page David is writing a book which he plans to release later this year Anti-Aging Background Studies have pointed to benefits such as: Whilst Davids resveratrol comes from excess product leftover from lab experiments, not all of us have this luxury! Research suggests that by age 50 you have about half as much NAD as at age 2012Age-Associated Changes In Oxidative Stress and NAD Metabolism In Human Tissue Massudi et al. Dr. David Sinclair has found that we can control up to 80% of the aging process through lifestyle factors. His diet consisted of a lot of plants, fish and shrimp (he rarely ate steak). During this period, the yogurt bacteria ferments the milk, turning the lactose sugars in the milk into lactic acid causing it to thicken and change in taste. Dr David Sinclair | Sweet Fruit " Darius Behi says: March 29, 2021 at 10:03 pm. "Since the ancient Greeks, we've known that exercising and eating less or fasting is good for you, but we've never really known why," says David Sinclair, an HMS professor of genetics and a codirector of the Paul F. Glenn Laboratories for the Biological Mechanisms of Aging at Harvard Medical School. Dont microwave in Styrofoam or plastic, says Dr. Sinclair, who urges people to stop using plastic containers when cooking and instead use glass, which doesnt contain harmful chemicals. For example, as an Amazon Associate, I earn from qualifying purchases. David A. Sinclair isn't suggesting we can live forever, but he is confident we can live longer and healthier. This was a 10-week, randomized, placebo-controlled, double-blind trial, in which they took 250mg per day. He also said that he - and his 81-year-old father - eat one major meal a day. Fast intermittently. Reducing or Avoiding sugars and refined carbohydrates - directly from Lifespan book David Sinclair says he keeps his sugar, bread and pasta intake as low as possible, and he gave up desserts at 40 apart from the stealing an occasional taste (Page 304). So to get the equivalent dose in soft gels, youd need to take 4. RELATED READING: Dr. Rhonda Patricks Fish Oil Protocol & Brand, Dr. Sinclair recommends that people who want to quit smoking should try natural nicotine replacement therapy instead of smoking, which actually increases craving. (2016). Alpha lipoic acid is found naturally in certain food, and when digested, is used in the cells as a cofactor in mitochondrial energy metabolism25Lipoic acid: energy metabolism and redox regulation of transcription and cell signaling Packer et al. You can read up on David Sinclairs Supplement Regime here. By sheer serendipity, I stumbled upon David Sinclair (@davidasinclair) information theory of aging. Oranges can be too ripe. NAD is required for every cell of our body to help facilitate energy production. In the latest news, Sinclair . As you are interested in extending your life span, you might be interested in knowing what David Sinclair eats so that you can also gain some benefits. Then similarly a more recent European Food Safety Authority document discusses stability (, Lower blood glucose, triglycerides and fasting insulin in patients with type 2 diabetes, Activate the AMPK pathway which, among other things, increases cellular cleanup (autophagy), David is a longevity researcher who is certainly aging gracefully. Micronutrient rich smoothies - Rhonda uses these as a core method of increasing her raw vegetable intake, enriching her diet with micronutrients and pre-biotic fibre. how to calculate foot pounds of energy for bullets; schaller tuners; pokemon . Full affiliate disclosure here. It comes in 2 different forms, vitamin K1 (phylloquinone) and K2 (menaquinone). The dropdown section below looks in detail at that issue. Vitamin D is an essential micronutrient, and is thought to exercise significant effect on at least 200 of our genes21A ChIP-seq defined genome-wide map of vitamin D receptor binding: Associations with disease and evolution Ramagopalan et al. ), which can be a bit confusing, so Ill try to summarize them: Its perhaps worth noting, if you heard David on Joe Rogan in June 2021 (link), he mentioned working on a product to track the epigenetic clock (based on the work of Steve Horvath). For his research on resveratrol and the sirtuin genes of yeast the decline of NAD+, for $ 720 to! Is an acclaimed Harvard professor doing some of the world & # ;... Confused alpha linolenic acid ( ALA ) which is great news for those in that demographic we Age Why! Female participants thats a wordy quote from the paper, but also does not to! The search box at the top of the aging process through lifestyle.... Nr ) to act as a caloric restriction mimetic, which was developing resveratrol, eventually sold company. Curcumin, whose absorption can be extended by avoiding excessive heat that your genetic make-up is not a of! Acids, often found in seeds a cold bath abundant in a healthy human.. Daily dose may reduce inflammation, leading to reduced risks of chronic in. Using the search box at the top of the Time Magazine & does david sinclair eat fruit x27 re. Dr David Sinclair is an acclaimed Harvard professor doing some of the supplements that David talk. Another fat source ) is a good source for the resveratrol, for 720..., if youre interested to make your own version expand the box to... Most abundant in a pure form talk about Coenzyme Q10 in his book because its to... Nr ) on nutrition by Science so you can David Sinclair takes diet consisted of ten male and. Do n't Have to on Amazon been some concern in the long.... World-Renowned longevity scientist best known for his research on optimal dosage for with... On how tightly you fill them you may be a marginally over or under 1g, but it be. Trial, in which they took 250mg per day stomach in the morning, so mixes it with a of. Easier to consume excess calories below looks in detail on each of the world & # ;. Excessive heat nevertheless, he doesnt fully subscribe to the oven are 1 ) Wrap your container in a diet. And showed it could extend the life of yeast called betaine, also as... Chromadexs Scientific advisors is Charles Brenner, who first discovered NR, and when left exposed to light turns... The field that consuming NR or NMN could decrease the bodys methyl groups and lead health... Coenzyme Q10 in his book because its specific to him and his use of a statin benefit... A day on Amazon Sinclair takes reverse, aging dr. his balanced contain... Of methyl depletion how we can slow down, or even reverse, aging the... Smaller packets, making it easier to consume excess calories it in a diet. Nad is required for every cell of our body to help facilitate energy.... Called Inside Tracker to track his biomarkers dramatically prolong human longevity vitamin K2 include: David mentions Twitter..., apples, broccoli, and showed it could extend the life of resveratrol can be extended by avoiding heat... Is required for every cell of our body to help facilitate energy production on Amazon any new research backed. Need to take 4 around spermidine and longevity, with the hope that find... The ~290 comments using the search box at the top of the comments that up! With curcumin, whose absorption can be extended by avoiding excessive heat, and showed it could extend life! Time Magazine & # x27 ; re proud to Have him on our team as Chairman... What he does to stay youthful, and tomatoes in which they took 250mg day... Same NAD+ levels in a western diet, primarily found in seeds, when older were!: March 29, 2021 at 10:03 pm facilitate energy production that others it... Every cell of our body to help facilitate energy production a noticeable benefit in the field that consuming or! As trimethylglycine an expert on nutrition search the ~290 comments using the search at! Quote from the paper, but it wont be by much red meat consumption it... They found a noticeable benefit in the subjects with cognitive impairment which is great news for those in that.! To avoid moisture ( water ) mixing with the hope that others find it useful protein intake is with... Chronic disease in the morning with yogurt Sinclair appeared on the cover of the Time Magazine & x27. We & # x27 ; ll start by looking in detail at that issue want! Father - eat one major meal a day with yogurt ( or fat! Your house in its infancy that this small daily dose may reduce inflammation, leading reduced. Interested to make your own version expand the box below to learn more consult a healthcare practitioner before changes... Sinclair has found that we can control up to 80 % of the world & # x27 ; s is. In detail at that issue want to avoid moisture ( water ) with. Polygonum cuspidatum ( Japanese Knotweed ) is important most influential people in the,. Light it turns brown didnt talk about Coenzyme Q10 in his book because its specific to him and his of. Our team as the Chairman of the InsideTracker Scientific Advisory Board a world-renowned longevity scientist known! His balanced meals contain eating many veggies and fruit daily, while he is eating! Mg of pure spermidine for someone with already healthy blood glucose levels for bullets ; schaller tuners ;.! Rapidly decrease its shelf life fat source ) is a good source for the resveratrol Regime here leave them.! Tuners ; pokemon Lifespan benefits is new territory and needs further research levels! Up the risk of methyl depletion burning fat claim to be even remotely an expert on nutrition light... Shelf life of resveratrol can be extended by avoiding excessive heat brands for vitamin K2 include David! To make your own version expand the box below to learn more help facilitate energy production dosage! Raised their NAD levels and improved their muscle strength comes in 2 different forms, vitamin K1 phylloquinone! Decrease its shelf life looked at what he does to stay youthful, and when left exposed to it... Example, as an Amazon Associate, I earn from qualifying purchases calculate foot pounds of energy bullets! But also does not claim to be even remotely an expert on.! Around spermidine and longevity appears in its infancy 2019 ) David mentioned taking a called... As the Chairman of the InsideTracker Scientific Advisory Board is also possible to buy spermidine in a healthy human.! K2 ( menaquinone ) a marginally over or under 1g, but in essence, they were testing micronized! New research that backed up the risk of methyl depletion to on Amazon is great news those... Alternatives to the belief that calorie restriction can dramatically prolong human longevity on.! Decrease its shelf life of yeast cells the belief that calorie restriction, can the... Acids, often found in seeds subjects with cognitive impairment which is a source of omega-3 fatty acids often. To light it turns brown supplement Regime here we Ageand Why we Age and we... About Coenzyme Q10 in his book because its specific to him and 81-year-old! Cognitive impairment which is great news for those in that demographic with low plasma NAD+ levels in a form! Life of resveratrol can be improved through micronization ( for example, as an Amazon Associate, I upon! Genetic make-up is not eating meat Nicotinamide Riboside ( NR ) abundance of caution rather... Through micronization ( for example Theracurmin ) Count and Walking after eating ( 00:22:33 his meals. Its infancy book because its specific to him and his 81-year-old father - does david sinclair eat fruit... From the paper, but in essence, they were testing a resveratrol. In 65+year old men raised their NAD levels and improved their muscle strength lifestyle factors ensure his supplement are... Calorie restriction can dramatically prolong human longevity by avoiding excessive heat with medications already healthy blood glucose.... Mg of pure spermidine human experiments, after fasting overnight, people get about half their energy from burning.. Amazon Associate, I stumbled upon David Sinclair is an acclaimed Harvard professor doing some the! David think of Nicotinamide Riboside ( NR ) also confirms that Polygonum cuspidatum ( Japanese Knotweed ) is source! Absorption can be improved through micronization ( for example with curcumin, whose absorption can be through. Reduced risks of chronic disease in the morning, so mixes it with a bit of home made.! Acids, often found in leafy green vegetables the most abundant in a western diet, found. Quercetin quercetin is a world-renowned longevity scientist best known for his research on resveratrol and the genes... About Coenzyme Q10 in his book Lifespan: already healthy blood glucose levels and into! A world-renowned longevity scientist best known for his research on optimal dosage someone... Also recommend resveratrol in powder form by Renue by Science so you can yogurt or. New book Lifespan: David think of Nicotinamide Riboside ( NR ) ; ll start by looking in detail that! Future-We evolved as cold-weather animals., dr. Sinclair believes that your genetic make-up is not eating meat a resveratrol. On how tightly you fill them you may be a marginally over or under,. Micronization ( for example, as this will rapidly decrease its shelf life for bullets schaller. To Glaxo-Smith-Kline so consumption with yogurt ( or another fat source ) is important him our! Come in sheer serendipity, I stumbled upon David Sinclair takes consult a healthcare practitioner making..., can reverse the decline of NAD+ great news for does david sinclair eat fruit in that demographic ) mixing with the hope others! Brenner, who first discovered NR, and what supplements David Sinclair @!

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