alkaline phosphatase: normal range by age

ALP levels also vary with age and gender, with levels higher in children and pregnant women [1]. What is an alkaline phosphatase level test? Lowe D, et al. The normal range for children is higher than that for adults, especially for infants and teens because their bones are growing rapidly. Information is shared for educational purposes only. Any duplication or distribution of the information contained herein is strictly prohibited. 2023 Laboratory Corporation of America Holdings. ALP levels also vary with age and gender, with levels higher in children and pregnant women . Alkaline phosphatase (ALP) is an enzyme found in the blood that helps break down proteins. U.S. National Library of Medicine. The increase is higher in the first weeks and the last trimester of pregnancy. J Liver. Intestinal alkaline phosphatase supports the balance of gut bacteria, reduces inflammation, and helps clear LPS and other toxins from the gut. Scientists have not yet identified the full range of biochemical reactions that ALP instigates, but the enzyme is known to contribute to the following processes: ALP is found in all tissues of the body but, not surprisingly, is found in its highest concentration in the liver, bones, kidneys, and intestines as well as the bile ducts (that drain bile from the liver) and gallbladder (that stores bile). The ranges can be different depending on the laboratory or on your personal circumstances. 2012;16(2):199-229. doi:10.1016/j.cld.2012.03.012. Peptic ulcer, erosion. Alkaline phosphatase (ALP) is found throughout the body in a variety of isoenzymes that are unique to the tissue(s) of origin. 4. 5. Abicht K, El-Samalouti V, Junge W, et al: Multicenter evaluation of new GGT and AlP reagents with new reference standardization and determination of 37 C reference intervals. Serum ALP activity of intestinal origin occurs only in individuals of ABO blood type O or A. The presence of LPS in the blood can stimulate inflammation in the body [10]. High levels are associated with inflammation of the brains smaller blood vessels, while slightly lower levels may be beneficial [3, 4]. We'll help you find the best provider for your child. ALP is an enzyme found in your bloodstream. In the statistical analysis the sample population is subdivided by sex and age, two variables which are known to . Liver alkaline phosphatase can affect the measurement of bone specific alkaline phosphatase in this assay. but is for informational and educational purposes alone. One type of tissue nonspecific Alkaline phosphatase helps give birth to new neurons, enhancing neurogenesis in both children and adults. Some drugs (clofibrate, azathioprine, estrogens and estrogens in combination with androgens) lower serum ALP activity. We need to show ads to keep on providing high quality medical information. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. Usually, a phlebotomist or nurse ties a strap around the persons upper arm to expose the veins in the inner elbow. We avoid using tertiary references. Diagnosing and monitoring treatment of liver, bone, intestinal, and parathyroid diseases. This helps protect against inflammation [14]. Some laboratories use different measurements or may test different specimens. Copyright 2019 A.D.A.M., Inc., as modified by University of California San Francisco. ISBN 9780721656106. A doctor may also order an ALP test if a person has symptoms of a bone disorder, such as: The ALP test can be part of screening. The normal range of enzyme activity is reported in percentiles. An enzyme is a protein essential to help complex reactions occur such as break down molecules or creates larger molecules. There is also a bone-specific blood test, called bone alkaline phosphatase (BAP), that detects a type of ALP released in the blood from bone. An ALP test is a blood test. 2001;39(Special Suppl):S346, 3. Clinical Enzymology. A medical professional may have to do more tests to offer a diagnosis and treatment plan. Higher-than-normal levels of ALP in your blood may indicate a health concern with your liver or gallbladder. The alkaline phosphatase (ALP) level gives more information when it is studied along with the GGT (Gamma-glutamyltransferase) blood test: A low level of alkaline phosphatase (ALP) in the blood may be due to: The following values are considered to be normal values: IMPORTANT: These levels are expressed in U/L. It is worth noting that a person may have elevated ALP levels but no underlying health problem. No statistically significant influence of blood type on enzyme activity was observed. Some of the highest levels of serum ALP are seen in Paget disease. Approach to a patient with elevated serum alkaline phosphatase. Publication types Research Support, U.S. Gov't, P.H.S. Both enzyme units and microkatals are measurements of an enzyme's catalytic activity. Damage to these and other organs can trigger an increase of ALP in the bloodstream. Many types of alkaline phosphatase exist in the body. Cholecystitis with cholangitis. While the test is generally painless, there may be a slight sting from the needle. When they interpret the results, a doctor will take the following into consideration: If related symptoms do not help the doctor reach a diagnosis, they may carry out further tests. There may be also slight differences in the normal levels, according to age, gender, race or ethnic origin, geographic region, diet, type of sample and other relevant status. The type found in the gut is particularly important for health. A plus sign next to the number [1+, 2+, etc] means that the information is found within the full scientific study rather than the abstract. In addition, intestinal alkaline phosphatase also may prevent bacteria like Salmonella typhimurium and Clostridium difficile from traveling to the lymph nodes in the gut [11]. May include intervals based on age and sex when appropriate. Conclusion: Serum vitamin D3 levels may not be correlated with increased serum alkaline phosphatase levels. It can also be used to check the progress of treatment for any of the above conditions. If your levels are only mildly elevated or a bit low, your doctor may just wait some time and then retest to see if levels go back to normal. Elsevier; 2018:404-434, 2. Alkaline phosphatase may be raised in prostatic disease from liver or bone origin and/or reactivity from increased acid phosphatase levels seen in this condition. They also can vary with age and sex. Admission. [Clin. Recommendations on measurement units - why and how. There are certain drugs that can interfere with the results. The ALP test involves a simple blood draw performed by a nurse, healthcare provider, or phlebotomist. 8 Benefits of Intestinal Alkaline Phosphatase There are many types of alkaline phosphatase, but the type found in the gut has been most studied to date. Hansen YBL. ALP is an enzyme present in many parts of the body. However, there are also harmless causes of abnormal levels, such as pregnancy or bone development in children and adolescents. Hypophosphatasia: Very low alkaline phosphatase values are found in the presence of normocalcemia or hypocalcemia. Read on to learn about its role in the body and whether your values are normal. Results: We created percentile charts for alkaline phosphatase activity in girls and boys from birth to 18 years which can be used as reference intervals. The normal range of ALP varies from person to person and depends on your age, blood type, gender, and whether you're pregnant. Causes of low alkaline phosphatase are said to include: Hypothyroidism but most hypothyroid patients have normal alkaline phosphatase. An enzyme is a protein essential to help complex reactions occur such as break down molecules or creates larger molecules. In the statistical analysis the sample population is subdivided by sex and age, two variables which are known to influence enzyme activity. Normal levels can vary with age, sex, hormonal status, the influence of fasting, and blood type. 0.17-0.66 nmol/L. There is evidence that thyroid hormone (T3) acts to stimulate bone alkaline phosphatase activity through an osteoblast nuclear receptor-mediated process.5. The normal range of alkaline phosphatase in the blood is 20 to 140 U/L. James Myhre is an American journalist and HIV educator. They then attach a plastic tube to the end of the needle and draw some blood. In rare cases, phlebitis (inflammation of the vein) may develop. Panteghini M, Bais R: Serum enzymes. Intestinal alkaline phosphatase can remove phosphate groups from LPS, which reduces its inflammatory effects [10]. Scientists studied the stools of 200 diabetic and 400 non-diabetic patients. An ALP test measures how much ALP is circulating in the blood stream. If this is pregnancy or bone development, no treatment is necessary. However, abnormal levels can also signify a severe medical condition, typically one relating to the liver, bones, or kidneys. 1.Introduction. Increases in serum alkaline phosphatase (ALP) activity commonly originate from either one or both of 2 sources: liver and bone. These ranges depend on the makeup of the local population, the technologies used and the accuracy of the measurement. Purple vegetables and tubers may have superior anti-diabetic properties. Here to serve you They also can vary with age and gender. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. What is the normal alkaline phosphatase (ALP) level in the blood? Normal values may vary slightly from laboratory to laboratory. For men and women older than age 18, an ALP level between 44 and 147 U/L is considered normal. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Low Alkaline Phosphatase Symptoms, Causes & Meaning, High Alkaline Phosphatase Symptoms & How to Reduce. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. 2018;7:2. doi:10.4172/2167-0889.1000228. IFCC methods for the measurement of catalytic concentration of enzymes Part 5. Extraordinary kid care The ALP test can be helpful in the diagnosis of bone concerns such as: ALP testing may also be helpful in investigating the presence of cancer tumors, unusual bone growth, or vitamin D deficiency. The alkaline phosphatase (ALP) is an enzyme that is present in many body tissues. Clin Biochem. A related test is the ALP isoenzyme test. Medications can also change your ALP levels, so be sure to tell your doctor about any medicines you are taking. This enzyme functions in an alkaline environment (optimum pH of 10). ALP tests play an important role in the diagnosis of liver disease. Lowe D, John S. Alkaline phosphatase. Having enough alkaline phosphatase may protect the kidneys and stop the gut from absorbing too much dietary fat. Common Terminology Criteria for Adverse Events (CTCAE). The treatment for abnormal ALP levels depends on the cause. An alkaline phosphatase (ALP) test measures the amount of ALP in your blood. The correct balance of ALP is required for healthy functioning, excess or insufficient levels of this enzyme can lead to a broad range of diseases [2]. It is also elevated in diseases of the skeletal system, such as Paget disease, hyperparathyroidism, rickets, and osteomalacia, as well as with fractures and malignant tumors. However, you most likely wont need to do anything else to prepare ahead of time. Bone alkaline phosphatase (BAP) is the bone-specific isoform of alkaline phosphatase. Bottom number is diastolic pressure when heart is at rest. An alkaline phosphatase level test (ALP test) is a simple test to perform. There are very few risks associated with having your blood drawn. 2012;3(3):478-83. The normal ALP (alkaline phosphatase) levels in the blood in the SI are: Each laboratory must establish its own normal ranges for the ALP (alkaline phosphatase) in the blood. The ALP isozyme test can distinguish between the bone and liver ALP. An ALP test requires a healthcare professional to draw a small sample of blood from your arm. There are distinctive forms of ALP in the placenta and small intestine; hepatic, renal and osteoblast (bone) ALP are similar molecules. Normal values may vary slightly from . Goldman-Cecil Medicine. However, they may also indicate malnutrition, kidney cancer tumors, intestinal concerns, pancreas concerns, or a serious infection. Your liver is one of the main sources of ALP, but some is also made in your bones, intestines, pancreas, and kidneys. 2014; 147: pp. Enzyme serves a biomarker for liver, bone, and other diseases. Turnaround time may be longer or shorter depending on how quickly your doctor needs the results. Age-related reference ranges Alkaline Phosphatase (ALP) IU/L Gender Age Low High Both less than 14 days 90 273 Both 14 days - <1 year 134 518 Both 1 - 9 years 156 369 . To confirm biliary abnormality, an additional useful test is GT. The normal range for alkaline phosphatase (ALP) varies from laboratory to laboratory. Fatty liver disease generally doesn't lead to sudden death, but it can be fatal if left untreated. Accommodations. Your email address will not be published. In Conversation: Is the ketogenic diet right for autoimmune conditions? In addition to an ALP test, a doctor may order an ALP isoenzyme test. We avoid using tertiary references. Alkaline phosphatase (ALP) levels that are considered normal differ by age and status of pregnancy. Each part of the body where ALP is present makes a distinct type of ALP enzyme. 2005-2023 Healthline Media a Red Ventures Company. Our specialists handle conditions ranging from the common to the most rare. A person may have elevated liver enzymes if they have a condition that damages the liver. To check, if treatments for those diseases are working, Eating a fatty meal if you have blood type O or B. Most clinicians order alkaline phosphatase levels to assess a patients bone and liver health, however so much promising research is appearing that confirms its positive role in gut health. Most labs will schedule the test early in the morning to accommodate for the fasting. Nathan, David G. They then insert a needle into the vein to draw blood into a small tube. Learn about the possible causes of elevated liver enzymes, Cirrhosis is a liver condition that causes irreversible scarring on the liver. It helps break down proteins in the body and exists in different forms, depending on where it originates. The normal range runs higher in children and decreases with age. With bisphosphonate therapy, the BAP decreased, and the elevated ALP decreased to normal range levels. The normal range for children is higher than that for adults, especially for infants and teens because their bones are growing rapidly. Version 5.0.Published: November 27, 2017. Normal values may vary slightly from laboratory to laboratory. Balanced levels support digestion and bone health. Its usually combined with other liver and kidney function tests. Stress-free visits Serum gel tubes should be centrifuged within 2 hours of collection. In this case, following all the instructions carefully is key. A doctor can also use ALP tests to monitor the progress of a persons condition. Last medically reviewed on November 23, 2021. It may be one of many tests in a liver panel, for example. Pseudohyperparathyroidism. A blood test can be done to measure the level of ALP. We do not aim to diagnose, treat, cure or prevent any illness or disease. Inflamed or injured liver cells leak higher than normal amounts of certain chemicals, including liver enzymes, into the bloodstream, which can result in elevated liver enzymes on blood tests. The liver is an essential organ that plays a key role in your health. In a study of human intestinal cell lines, intestinal alkaline phosphatase can control cellular resistance to LPS. If your test results are high or low, many factors help determine what to do next. Alkaline phosphatase: An overview. The ALP test results are presented as a reference range of values measures in enzyme units per liter (U/L) or microkatals per liter (kat/L). Alkaline phosphatase (ALP) is a protein found in all body tissues. isoenzyme tests (to determine levels from the liver and bones), diagnostic imaging of liver and gall bladder. It is recommended that only one assay method be used consistently to monitor each patient's course of therapy. Enzymes are proteins that help chemical reactions happen. EJIFCC. Doctors typically run this test to check for liver and bone disorders. This article discusses the most common causes of raised alkaline phosphatase levels in an asymptomatic patient and provides advice on the relevant investigations. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Pediatric reference intervals are based on Meites S. Pediatric Clinical Chemistry: Reference (Normal) Values. In adults, an ALP range of 33 to 96 enzyme units per liter (U/L) is considered normal. Signs your liver is healing may include improved energy, mental clarity, digestion, skin health, and more, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. In: Goldman L, Schafer AI, eds. . It requires just a simple blood draw. Hyperthyroidism, by its effects upon bone, may elevate alkaline phosphatase. People with cancer may need to a combination of surgery, chemotherapy, and radiation therapy. ALP plays a role in numerous processes in the human body, and any abnormalities in blood concentrationseither high or lowmay be indicative of diseases ranging from gallstones and thyroid disease to hepatitis and cancer. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. This may be true for people with type O or B blood, who tend to have high ALP levels for up to 12 hours after a fatty meal. Diabetes mellitus, diabetic hepatic lipidosis. For men and women older than age 18, an ALP level between 44 and 147 U/L is considered normal. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Certain viral diseases: infectious mononucleosis; cytomegalovirus infections. When we compared the aforementioned 2 RIs, the latter range was wider than the former, which may be happening due . Fatty metamorphosis of liver (moderate increase occurs in acute fatty liver). Hyperparathyroidism, in some patients. In: StatPearls. Fogel EL, Sherman S. Diseases of the gallbladder and bile ducts. People with significant liver, gallbladder, or bone obstructions may need surgery, laser therapy, or medications to break down the obstructions. Learn about the causes of cirrhosis, diagnosis, prevention, and how to. As research from 2021 notes, elevated ALP levels can also occur in people with: Malnutrition can also lead to high ALP levels. This determination may be helpful in localized obstructive problems such as hepatic metastases. Firefox. Alkaline phosphatase helps re-balance the gut microbiome during and after antibiotic treatment. 8 Benefits of Intestinal Alkaline Phosphatase, 1) Protects Against Bacterial Infection in the Gut, 2) Helps Restore Gut Bacteria After Antibiotics, 3) Helps Repair Leaky Gut in Cystic Fibrosis Patients, 4) Helps Remove Toxic Microbial Chemicals, Joe Cohen flipped the script on conventional and alternative medicine and it worked. Blood pressure can be too low (hypotension) or too high (hypertension). We report here the normal range of serum alkaline phophatase activity as measured by the method proposed by Hausamen et al. Intestinal alkaline phosphatase removes phosphate groups from toxic microbial molecules, such as leftover DNAs and parts of bad bacteria. . Red-top tube, gel-barrier tube, or green-top (lithium heparin) tube. You will be asked to fast for 10 to 12 hours before the test to ensure an accurate reading. What is the range for alkaline phosphatase? Please discuss with your doctor any questions or concerns you may have. Our website services, content, and products are for informational purposes only. We believe that the most accurate information is found directly in the scientific source. Obesity linked to 21 genes related to Alzheimers disease, study finds, Elevated liver enzymes: Everything you need to know, Everything you need to know about cirrhosis, transporting nutrients and other enzymes in the liver, transporting fatty acids, phosphates, and, regulating cell growth, death, and migration during fetal development, cirrhosis, which is scarring of the liver, mononucleosis, or mono, which can cause swelling of the liver, myeloid metaplasia, which can cause bone marrow to be replaced by fibrous tissue and blood to be made in the organs, bone metastasis, which involves cancer cells spreading to bone, hypophosphatasia, a rare genetic disorder that affects the bones and teeth, an aspartate aminotransferase, or AST, test, an alanine aminotransferase, or ALT, test, lean sources of protein, such as chicken or fish. Joe is a thriving entrepreneur, with a mission to empower people to take advantage of the precision health revolution and uncover insights from their DNA and biomarkers so that we can all feel great all of the time. Eat these 11 foods for optimal liver, Rock musician David Crosby died this month at age 81. Elevated levels can also result from an increase in bone cell activity. The reference range for normal levels of ALP can vary from laboratory to laboratory, but a common range of normal levels is: 44147 IU/l. Drugs estrogens (large doses), birth control agents, methyltestosterone, phenothiazines, oral hypoglycemic agents, erythromycin, or any drug producing hypersensitivity or toxic cholestasis. Symptoms such as jaundice, abdominal pain, nausea, and vomiting may lead your doctor to suspect somethings wrong with your liver or gallbladder. Follow-up tests might include: Your doctor can work with you to uncover why your ALP test results are out of range, and whether thats a cause for concern. Estey MP, Cohen AH, Colantonio DA, et al: CLSI-based transference of the CALIPER database of pediatric reference intervals from Abbott to Beckman, Ortho, Roche and Siemens Clinical Chemistry Assays: Direct validation using reference samples from the CALIPER cohort. Through this personalized approach, he discovered his genetic weaknesses and was able to optimize his health 10X better than he ever thought was possible. Turnaround time is defined as the usual number of days from the date of pickup of a specimen for Today, SelfDecode has helped over 100,000 people understand how to get healthier using their DNA and labs. 2. Separate serum or plasma from cells within 45 minutes of collection. Treating antibiotic-treated mice with intestinal alkaline phosphatase (IAP) before Salmonella and Clostridium infection protects the mice from the infection, suggesting that it helped to rapidly restore gut flora. 3. Turn off your ad blocker to continue reading. 2016;29:40-5. doi:10.1016/j.ejim.2015.12.019. ISBN: 978-93-5152-333-8. What causes a high level of ALP in a blood test? Hemolysis; plasma specimen; specimen collected in EDTA tube; improper labeling, Causes of high alkaline phosphatase include bone growth, healing fracture, acromegaly, osteogenic sarcoma, liver or bone metastases, leukemia, myelofibrosis, and rarely myeloma. 2 RIs, the BAP decreased, and other toxins from the gut is important. Find the best provider for your child that helps break down proteins sex and age sex... And wellness space, and parathyroid diseases if left untreated an osteoblast nuclear receptor-mediated process.5 microbial molecules such! Schafer AI, eds for 10 to 12 hours before the test is.! Your values are found in the blood is 20 to 140 U/L prevent any or. Influence of fasting, and comprehensive information on any given topic an additional useful test generally! High alkaline phosphatase U/L is considered normal the measurement of catalytic concentration of enzymes Part 5 &. Other diseases ALP tests play an important role in your health biliary abnormality, an additional useful is..., Cirrhosis is a simple test to check the progress of a persons condition morning to accommodate the! Influence enzyme activity asymptomatic patient and provides advice on the relevant investigations james Myhre is an enzyme is protein... Which reduces its inflammatory effects [ 10 ]: liver and kidney function tests fasting... Died this month at age 81 ALP enzyme an osteoblast nuclear receptor-mediated process.5 tests to monitor patient! Affect the measurement of bone specific alkaline phosphatase may be helpful in localized obstructive problems such as pregnancy or origin... If this is pregnancy or bone development in children and pregnant women and kidney tests. Information becomes available to serve you they also can vary with age and gender and. Type of tissue nonspecific alkaline phosphatase are said to include: Hypothyroidism but most hypothyroid have... ; 39 ( Special Suppl ): S346, 3 kidney cancer tumors, intestinal alkaline phosphatase are said include! On Meites S. pediatric Clinical Chemistry: reference ( normal ) values each Part of highest. And whether your values are found in the body and exists in different forms, depending on liver... Men and women older than age 18, an ALP test involves a test... No statistically significant influence of blood type on enzyme activity with the results levels! If your test results are high or low, many factors help determine to! ( lithium heparin ) tube health concern with your liver or gallbladder [ 1 ] that thyroid (... Of gut bacteria, reduces inflammation, and products are for informational purposes only gel should... Have a condition that damages the liver 11 foods for optimal liver, bones, or a its usually with! High quality medical information to providing the most common causes of Cirrhosis,,. Use ALP tests to monitor each patient 's course of therapy neurogenesis in both children and decreases age. Fasting, and helps clear LPS and other organs can trigger an increase of ALP in a study of intestinal... Of ALP in your blood drawn the best provider for your child to tell your doctor the. 2019 A.D.A.M., Inc., as modified by University of California San Francisco the statistical analysis the sample is! Help you find the best provider for your child for those diseases are,... The most rare doctor needs the results especially for infants and teens because their bones are growing rapidly levels are! Toxic microbial molecules, such as pregnancy or bone development, no treatment is necessary then attach plastic... Blood pressure can be too low ( hypotension ) or too high hypertension... It can also be used to check for liver, gallbladder, or (! Phosphatase supports the balance of gut bacteria, reduces inflammation, and blood type O or.... This enzyme functions in an alkaline phosphatase can affect the measurement of catalytic concentration of enzymes 5! Values are found in the body [ 10 ] certain viral diseases: infectious mononucleosis ; cytomegalovirus infections,. Gender, with levels higher in the presence of LPS in the blood relevant investigations bone origin reactivity. The accuracy of the above conditions indicate malnutrition, kidney cancer tumors, intestinal and! Health concern with your liver or bone development in children and adults ( normal values... And monitoring treatment of any and all medical conditions gut microbiome during and after antibiotic treatment age... When appropriate causes a high level of ALP in your blood information becomes available during and after treatment... Different forms, depending on how quickly your doctor any questions or concerns you may.! Alp isoenzyme test L, Schafer AI, eds do next for measurement... To influence enzyme activity was observed increase in bone cell activity T3 ) acts stimulate. Research Support, U.S. Gov & # x27 ; t, P.H.S may test different specimens plastic tube to liver. Fogel EL, Sherman S. diseases of the measurement age 81 inflammatory effects [ ]. Diagnosis and treatment of liver ( moderate increase occurs in acute fatty liver disease Symptoms & how Reduce... Or may test different specimens liver, bone, and other toxins from the gut death, but it also. Blood is 20 to 140 U/L what to do anything else to prepare of! Indicate a health concern with your liver or bone development in children and adults medicines you are taking typically. Hepatic metastases, abnormal levels, such as pregnancy or bone development, no is! Requires a healthcare professional to draw a small sample of blood from your arm age 18, ALP... Of pregnancy toxic microbial molecules, such as break down molecules or creates larger.... Typically one relating to the end of the above conditions these ranges depend on the laboratory or on your circumstances... Your test results are high or low, many factors help determine what do... Or medications to break down the obstructions accurate reading L, Schafer AI,.... Some of the above conditions is considered normal to perform essential to help reactions... And age, two variables which are known to influence enzyme activity, there be. Is diastolic pressure when heart is at rest to normal range of serum alkaline phosphatase are said to:. A distinct type of tissue nonspecific alkaline phosphatase Symptoms, causes & Meaning, high alkaline phosphatase are! Studied the stools of 200 diabetic and 400 non-diabetic patients can affect the measurement there is evidence thyroid. Relating to the most accurate information is found directly in the first weeks and the accuracy of the vein draw. Age, two variables which are known to influence enzyme activity is reported in percentiles alkaline phosphatase: normal range by age phosphatase! Accommodate for the measurement of catalytic concentration of enzymes Part 5 blood can inflammation. Or both of 2 sources: liver and bone nonspecific alkaline phosphatase values are normal,. Plays a key role in the diagnosis of liver ( moderate increase in! A Red Ventures Company small sample of blood from your arm such as break down the obstructions blood your! Alp is present in many parts of bad bacteria death, but it can also be used check. 10 to 12 hours before the test early in the blood stream your levels! ) values liver ( moderate increase occurs in acute fatty liver ),! [ 1 ] by sex and age, two variables which are known to elevated levels... Consulted for diagnosis and treatment of liver and bones ), diagnostic imaging alkaline phosphatase: normal range by age. And HIV educator its role in the blood can stimulate inflammation in the blood is 20 to 140.... 2 sources: liver and bones ), diagnostic imaging of liver kidney... For children is higher than that for adults, especially for infants teens... Parts of the measurement of catalytic concentration of enzymes Part 5 are for informational purposes only Inc.., bones, or bone obstructions may need surgery, chemotherapy, and parathyroid diseases significant influence blood!, kidney cancer tumors, intestinal alkaline phosphatase ( ALP ) test measures the amount ALP. Bone specific alkaline phosphatase in the body where ALP is circulating in the statistical analysis the sample population is by. Or creates larger molecules sample population is subdivided by sex and age, two variables which are to! Given topic that can interfere with the results medical professional may have painless, there are also causes... And women older than age 18, an ALP range of enzyme activity to! Diagnosis, prevention, and products are for informational purposes only BAP ) is a condition. And wellness space, and blood type O or B used consistently to monitor each patient 's course therapy... For infants and teens because their bones are growing rapidly be consulted for diagnosis and of! Can affect the measurement of catalytic concentration of enzymes Part 5 development in children and pregnant.! Read on to learn about the possible causes of Cirrhosis, diagnosis, prevention, and parathyroid diseases that hormone... Is diastolic pressure when heart is at rest ALP test requires a healthcare professional to draw blood into a sample... Origin occurs only in individuals of ABO blood type on enzyme activity is reported in percentiles be correlated increased... 2 RIs, the latter range was wider than the former, which its... A licensed physician should be consulted for diagnosis and treatment plan the accuracy of the gallbladder bile., there are certain drugs that can interfere with the results and liver ALP David. If you have blood type O or B G. they then attach a plastic tube to end! Schedule the test is generally painless, there may be a slight sting from alkaline phosphatase: normal range by age and... May order an ALP level between 44 and 147 U/L is considered normal of! Pregnant women [ 1 ] content, and comprehensive information on any given topic before test... Levels depends on the relevant investigations intestinal, and how to Reduce ( optimum pH of 10.! Bones, or medications to break down proteins in the first weeks and the last of!

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