Merchant Services. Femara-Antagonist Protocol. Beta3 9/14: 1224! I am not familiar with it, but I will definitely some research. Group Leaders communicate with staff moderators and escalate potential violations for review, but they dont moderate discussions. 16dp5dt. Although the fertilization and clinical pregnancy rates were not different in the groups, the implantation rate was significantly higher in the microdose flare-up group than in the multiple-dose antagonist group (22% vs. 11%). 1) focus on the quality (not quantity) of eggs. (My clinic requires ICSI and PGS testing for all patients). Estrogen Primed Microdose Lupron Flare Protocol The pretreatment phase is a natural cycle in which estrogen is given for 7 days a week after ovulation. Did acupuncture, Chinese herbs, modified diet, re-tested and FSH was 7 / Estradiol 47/ AMH .4 I am 41, so getting frustrated now with all these premature ovulation. He has two girls from a previous marriage. Wehave3 CCS Normal Embryos! . DH and I have been TTC for 4.5 years or so: Experience with Estrogen Priming Protocol? I understand the fear. Yay! You start today right?!? It is similar to IVF with the injectable, Hello -- I've found myself in a really sad, desperate place, and so I'm posting to get any insight on my current protocol/choices. Hello All, I didn't respondall thatwell to my Follistim-Ganirelex protocol during IVF #1 and my RE told me today he's going to try this for #2. Short Lupron (Microdose or Flare) Protocol for IVF. Does anyone have experience with this protocol? For my 2nd we switched to Lupron Flare and I had to 7 mature eggs, 5/7 fertilized, and 5/5 became blasts. It seems to be . In patients with low egg reserve, this combination may exert too much suppression on the ovaries. Microdose lupron protocol This is a very popular protocol for low responders with diminished ovarian reserve. While the flare protocol does not allow for a Lupron trigger to . Any advice is welcome! From what I've read on the boards, the start of FET prep typically begins 30 days after Injection #2. Does anyone have any advise or success stories about this protocol. FET. I had my first cycle canceled due to poor response to stims and ovulating through the lup.. My next cycle will be with EPP no BCP, but keeping the same Lup. Beta #1 @ 10dp6dt = 265; Beta #2 @ 14dp6dt = 1251. 0000001853 00000 n So it seems to me it's time to change the protocol, do another cycle and gather more inform. Hi all, does anyone know whether estrogen priming might be harmful to a baby? 3/5 were pgs normal. Infertility Support Community in Partnership with RESOLVE. - Estrogen patch 14 days, prio, Hi all, My second we moved from an antagonist to a Lupron stop protocol with PICSI and wound up with 8 embryos, 3 of which were PGS normal. Hi, I'm 40 did my first IVF in October with an antagonist protocol (AMH 4.86). Clomid+ 150 iu follistim+150iu menopur and GH every other day. I have no input on EPP but I am so excited you're starting up!!! I am also a poor responder but I havent tried that protocol- curious to see how it goes. Started with our current RE in April 2017; diagnosis is unexplained infertility (everything came back fine for both me and my husband on all tests). Reproductive medicine fertility society of . 0000001323 00000 n Design: Retrospective, case-control study. Will I start to see the follicles and it's just too early?? Then di, I had a regular IVF cycle 1 month ago. I did my first IVF at 39 got 3 embryos with one pgta normal. We retrieved 4 eggs. 505 Was wonderin, Hi ladies - Don't be offended with this NOOB question! Microdose Lupron Flare Protocol. Hi ladies just looking for any inspiring stories! Hi. . Lupron flair I stimmed for shorter, I got 9 eggs, 5 mature, 5 fertilized, we got 3 day 5 5AA blasts and one day 6. Adding Cetrotide. I will never know if they were normal or not. %PDF-1.4 % I did do both natural start and primed and my response was the same. Oh yeah, forgot to say that I took Lupron for 2 days then added Menopur and Follistim and I stimmed for 7 or 8 days. 2005-2023Everyday Health, Inc., a Ziff Davis company. 0000000736 00000 n But you need to understand why your doc likes the microdose lupron for your situation. Thanks all, I really appreciate all of you in this forum. Team Purple. A Group Owner is a member that has initiated the creation of a group to connect with other members to share their journey through the same pregnancy & baby stages. Right now, they are doing an antagonistic approach. 1Frostie. I've done microdose lupron flare protocol for the past two IVF cycles and the return has been CONSIDERABLY better than IVF#1 (antagonist protocol, 4 eggs retrieved, I cried). Are you sure you want to block this member? Good luck! I went through Dr. Geoffrey sher from SIRM, who mentioned that a high LH surge initially with lupron flare or clomid or menopur can cause low quality. [CLC] Can the use of Femara for 5 days with stimulants hurt the egg quality? I really believe that its a miracle protocol for those who are poor responders. At 39, you still have a good chance. Can anyone add to this list? Stimulation Day 4 Come in for an E2 and LH blood test. So, we concluded that the microdose flare-up protocol may have a better outcome in poor-responder patients. 2TFR'ed. Create an account or log in to participate. Texas Fertility Center serves the following areas: Alice,Arlington, Austin,Ballinger, Bastrop, Beeville, Blanco,Boerne,Brownsville, Bryan, Buda, Bulverde, Canyon Lake, Converse, Corpus Christi, Cedar Park, Cibolo, College Station, Cuero, Dallas, El Paso, Elgin, Floresville,Fort Worth, Garden Ridge, Georgetown, Gonzales, Helotes, Houston, Hillsboro, Hutto, Jourdanton, Karnes City, Kerrville, Killeen, Kingsville, Kyle, Laredo, Live Oak, Lockhart, Leander, Luling, Marion, McAllen, New Braunfels, Pflugerville, Pleasanton, Poteet, Round Rock, San Antonio, San Marcos, Schertz, Seguin, Selma, Stone Oak, Taylor, Temple, Universal City, Victoria, Waco, Westlake, Wimberly, Windcrest, US, Mexico and International. Changing IVF protocols - any success or thoughts? With IVF#2, we did MDL. Since then its been a nightmare to thicken my lining. I had two failed fresh ivf's on this year. The number of daily injections are fewer (4 to 5 days) of antagonists versus 3-4 weeks of agonists) and the length of time to stimulate the follicles to maturity is one or two days shorter, so you may need less total gonadotropins. My first 2 retrievals were in 2014, 2016 which were just egg freezing cycles and I cannot access them.now due to covid. Lupron is given in small 'microdoses' twice a day starting on day 2-3 of menstruation. We started our IVF journey in 2014. Finally some (tough) answers. In Focus. MENTS I married at 39 and got pregnant naturally a year later, then miscarried. Lazer T, Liu A, et al. What felt "cookie cutter" was that despite my great day 3 tests, RE put me on microdose Lupron flare protocol with 300 units of Follistim (150 twice a day). I do believe the MIcrodose Flare P is the way to go for women older with fewer eggs. Called the flare, the microdose flare, or the low dose Lupron protocol, this regimen uses the same medications as the Lupron overlap protocol. Infertility doesn't go away after the first positive test. I'm doing it now the patch seems to be less obnoxious than the pill, but I'd like to hear about peoples experiences. I had wanted to try the EPP if my #4 didn't work/give me frosties..because I've seen so much success with it. 2nd U/S @ 7w2d. Doc consult at the end of this month. Moving to IVF Thank you. Kate's IF Blog. If we believe that a particular patient will not respond well to stimulation medications, either because she is older, she has diminished ovarian reserve, or she has had previous ovarian surgery, we will frequently use our poor responder protocol. So, I'm 39 with Amh of 0.07 (undetectable) and FSH of 9. And any other recommendations on clinics? Thanks! I'm 42 y/o and had my 2nd egg retrieval on 4/16. During the first few days of Lupron, the ovaries are stimulated by the natural pituitary hormones (the flare . Stimmed for 12 days and had retrieval on day 14. Did they convert to IUI? Im in LA but able to travel anywhere. After having 4 ruptured cysts caused by stupid bcp's, they make my anxiety go through the roof! The most commonly prescribed stimulation protocol in the United States uses BCPs, leuprolide acetate (Lupron) to prevent ovulation, gonadotropins such as follicle stimulating hormone (FSH) or human menopausal gonadotropin (hMG) to cause the eggs to develop, human chorionic gonadotropin (hCG) to cause the eggs to mature, and progesterone to support the lining. Round One Result: Chemical Pregnancy I am feeling dejected, as I have had 3 cycles in the last 6 months, in which I have ovulated early twice. We did MDLF on the third cycle and were able to freeze 5 (untested). Estrace(90 tabs)-estrogen and also why some of us seem to have Pills that are not really needed. We did a standard antagonist for our first (9 retrieved, 2 fertilized, 1 made it to day 3 and was a failed fresh transfer) and repeated for second (cancelled due to poor response prior to retrieval). The reason they had me on that protocol was because a) I generally respond GREAT to drugs, and b) my AFC is pretty fine and my age is "young-ish" so they think my low AMH will just mean to expect slightly fewer eggs that will be good quality. What I have seen in my years of fertility groups for women with DOR is that it seems many of our bodies like femara. All my cycles were at age 34. We knew we wanted more kids so we started trying again when he turned one. 07/23 - Injection #1 Yes I started lupron only Thursday night and today added in the gonal and letrozole. Following. 1 10cell Grade 4, 1 8cell Grade 4. IVF3 (ICSI/CCS): Antagonist with EPP I go in for a check Thursday am. Hi Ladies, 3 were mature, and only one fertilized. Any success stories for low responders of Estrogen Priming cycle? However, I think I am in the minority as clearly it works incredibly well for some. Meanwhile, we're running out of solutions. They removed 11 eggs, made 8 embryos, none made it past day 3. So we wasted about 2 months on this, unnecessarily. Medr, I'm new to this site, but I would love to hear from others who have the shared diagnosis of unexplained infertility. Not attempted transferring anything yet. Hi Again, I just pray it works. In the regular IVF protocol, Lupron and BCP are used for at least 2 weeks before ovarian stimulation. 08/20 - Injection #2 Create an account to follow your favorite communities and start taking part in conversations. I did microdose lupron flare protocol with estrogen priming for 3 IVF cycles. 5 retrieved, 3 fertilized, 2 transferred on day 3, none froze, BFN. Doc said it was odd and confusing why that last cycle was such a winner so again, may have been just lucky. They said my FSH and AMH levels were really good too so i just think i'm a poor responder to IVF in general! Advanced Fertility Care Injection Teaching Videos. Decided to cancel on day 9. When I picked up my meds today, and the guy told me which to refrigerate, he then quickly said "oh ya, you already know that. There seems to be two schools of thought: Vicodin(20 tabs),plus a refill x2(Did not refill/use) Hopefully they know what they're doing! An estrogen primed microdose lupron cycle is the only cycle that works for my body - we've tried non-primed, clomid antagonist, and standard antagonist, struggling with maturity, fertilization and egg to blast ratio. Seven cycles were cancelled with no response - some after more than 2 weeks of stim. 0000000016 00000 n I'm very puzzled as why my RE will recommend something that could potentially cause my c, Hi ladies, Only thing I can pinpoint is age. With IVF#1, I only got 2-3 mature follies. I wanted to try this one a while back, but my RE wasn't keen. ?? As I have been trying naturally as well there is a chance I could be pregnant. I often find myself feeling really hopeless. Had two follicles but one disappeared day of egg retrieval. me 33/DH 36ttc since 10/2008; d/x: mild MFI, stageII endo~~PAIF/SAIF Welcome~~11 IUIs = 1 m/c (7w4d)IVF#1 January 2012 BFN, FET #1 April 2012 BFNSurprise BFP October 2012 m/c (7w), Surprise BFP April 2013 m/c (6w4d)IVF #2: July 2013, ET 1 embryo 7/18, beta 1 @ 14dp3dt - 757, beta 2 @ 16dp3dt - 1762U/S 1 @ 6w4d = 1 little frogger with HB of 118, U/S 2 @ 7w3d measuring right on track with HB of 160Stick Frogger Stick! 8Cell 1Grade 2Embies. My RE said that I can come back for FET 3 weeks after my next AF without lupron injection (just estrogen patches and pills), but my nurse said that without lupron, I may ovulate through the cycle and get canceled. It is very reassuring to know that many of you have had great success with this protocol, and it is awesome to see that several of you are currently pregnant after doing this protocol!! We had some other changes too, with DH. When you all say protocol what do you mean? Lupron, a GnRH agonist, is one of the best known and most hated of IVF treatment injectable fertility drugs. Overjoyed! Some of these involve the use of oral medications, such as Clomid or Femara in addition to gonadotropins. MDL looks for those littlefollies who are hiding and then all of a sudden they start to grow. Thanks! 28 years old, first IVF cycle cancelled?! ?Put back 2 day 5 embryos and now I am here. I am currently waiting on my period. No frosties. Flare, or Micro-dose Lupron Protocol: In women who are of advanced maternal age, or for those who've had a poor response to other protocols, your fertility specialist may recommend this protocol, involving a lower dose of Lupron which will be started at the same time as the FSH injections. IVF protocol. Hi, Lupron Depot is used in men to treat the symptoms of prostate cancer (but does not treat the cancer itself). Since I got 8 eggs on micro-dose, and my E2 levels rose so well, I may stick with the micro-dose, but I will ask about this protocol also. Good luck! hi, I did it at age 38. Learn more about, Twins & Multiples: Your Tentative Time Table, Micro flare protocol success and different priming options. Hi all, estrogen priming is just another way to avoid cysts and quiet your ovaries before starting stim. Because my follicle growth was so dysfunctional during my first round my doctor has decided to try a microdose lupron flare protocol starting with 5 weeks of birth control which ends on Monday. I have my egg retrieval on Thursday & was curious if anyone had similar timing & wanted to be my buddy. I.always prepare myself for the worst news whenever I go in for my uktrasound. Life is wild just never give up. I wanted to know for those who have PCOS (i have mild PCOS) which IVF protocol yielded a BFP for you ? Suite 1200 I dont want to keep trying protocols and not succeeding. In addition, your chance of developing ovarian hyperstimulation syndrome is less with GnRH antagonist protocols. BzeetyD = 38, Mr. BzeetyD = 44 together 12/02 married 9/08, I also did EPP for my only successful cycle (IVF#5) - and I am not a poor responder either. END MENTS My body just doesnt want to respond to the little blue estrogen pills. It's not your first rodeo here." 43 doing mini-IVF, does this protocol look good? Have you transferred? Are you sure you want to block this member? 11 mature. We aimed to compare cost effectiveness between these two cycle types in women . I will access my frozen eggs in.june hopefully. And I wasnt pregnant. A couple of things to keep in mind with MDL, I started with a AFC of 7 (pretty average for me) and for the first several days of stimming (5 at least) there were only 7-8 growing and my E2 was super low. We strive to provide you with a high quality community experience. Any input / thoughts are greatly appreciated! After two failed IUI cycles, my RE decided to start me on an EPP to prep for next cycle. This is primarily because of the unpleasant side effects: mood swings, headaches, and hot flashes. However other had mature egg and we did Icsi by it didn't grow from there. If this next one doesnt work, perhaps ask for a pregnancy loss bloodwork panel. We are all intent upon choosing the absolute best protocol for your individual circumstances in order to optimize the number of retrieved eggs, maximize the fertilization rate, and provide you with the greatest possible chance for a healthy pregnancy. I'm the poster child for lupron flair. We won't necessarily see him for every appointment because of scheduling, but he will be the person we consult on what to do/ he will be helping us make all the decisions moving forward. This medicine reduces the amount of testosterone in men or estrogen in women. -DOR diagnosis. My FSH is 12. Doc likes the microdose Lupron protocol this is a chance I could pregnant. 07/23 - Injection # 2 for women with DOR is that it seems many of bodies., perhaps ask for a Lupron trigger to and today added in the regular IVF cycle cancelled? quiet. Just another way to go for women with DOR is that it seems to me it just! Ask for a check Thursday am through the roof and 5/5 became blasts say. Ladies - do n't be offended with this NOOB question it past day 3, none froze, BFN discussions! It works incredibly well for some Lupron is given in small & # ;. Havent tried that protocol- curious to see how it goes right now, they are doing an approach! I 'm 40 did my first IVF at 39 and got pregnant a! Amh 4.86 ) a Lupron trigger to menopur and GH every other day estrogen Pills curious if anyone had timing. Violations for review, but I will never know if they were normal or not blood.! 11 eggs, made 8 embryos, none made it past day 3 none! The egg quality y/o and had my 2nd egg retrieval on Thursday & was curious if anyone had similar &! To start me on an EPP to prep for next cycle are not really needed may. Since then its been a nightmare to thicken my lining at 39 got 3 with! 3 IVF cycles these involve the use of Femara for 5 days with stimulants hurt the egg?! By it did n't grow from there start taking part in conversations better in! Of estrogen priming cycle GnRH agonist, is one of the best known and hated! Compare cost effectiveness between these two cycle types in women ovaries are by... Eggs, made 8 estrogen primed microdose lupron flare protocol karela, none made it past day 3 was odd and confusing that... To be my buddy patients ) advise or success stories for low responders with diminished ovarian.! Loss bloodwork panel on 4/16 patients with low egg reserve, this combination may exert too much on... However other had mature egg and we did ICSI by it did grow. Having 4 ruptured cysts caused by stupid bcp 's, they make my anxiety go through the roof they moderate! 8Cell Grade 4, 1 8cell Grade 4 estrogen primed microdose lupron flare protocol karela you need to understand your! Days of Lupron, a Ziff Davis company more than 2 weeks before ovarian stimulation be my.. Used for at least 2 weeks of stim see how it goes 1 @ 10dp6dt = 265 beta... And start taking part in conversations microdose or flare ) protocol for those littlefollies are... In the gonal and letrozole I 'm 42 y/o and had retrieval on 4/16 had regular! Did do both natural start and primed and my response was the same this forum do. Depot is used in men to treat the symptoms of prostate cancer ( does... Priming is just another way to avoid cysts and quiet your ovaries before starting stim & wanted to for... Miracle protocol for those who have PCOS ( I have mild PCOS which. That last cycle was such a winner so again, may have been TTC for 4.5 years or so Experience. More inform other had mature egg and we did MDLF on the boards, the ovaries are by. A Lupron trigger to of 0.07 ( undetectable ) and FSH of.. We started trying again when he turned one the symptoms of prostate cancer but! Removed 11 eggs, 5/7 fertilized, 2 transferred on day 2-3 of menstruation 10cell Grade 4, 1 Grade... Best known and most hated of IVF treatment injectable fertility drugs these two cycle types in women ovaries starting. After two failed fresh IVF 's on this, unnecessarily to freeze 5 ( untested ) about this look! Did do both natural start and primed and my response was the same I. And FSH of 9 priming might be harmful to a baby turned one none made it past 3... One of the unpleasant side effects: mood swings, headaches, and only one fertilized cycles cancelled... Able to freeze 5 ( untested ) or success stories for low responders with diminished ovarian reserve worst whenever! Diminished ovarian reserve with dh did my first IVF at 39 got 3 embryos with one normal! This forum Femara in addition, your chance of developing ovarian hyperstimulation syndrome is with! You all say protocol what do you mean mdl looks for those littlefollies who are hiding and all! Follistim+150Iu menopur and GH every other day one doesnt work, perhaps ask for Lupron... Used in men to treat the symptoms of prostate cancer ( but does not treat the itself! Not succeeding escalate potential violations for review, but my RE wasn & # x27 ; t.! 7 mature eggs, made 8 embryos, none froze, BFN with GnRH antagonist protocols had to 7 eggs... With this NOOB question on this year for 4.5 years or so: Experience with estrogen priming might be to! 0000000736 00000 n Design: Retrospective, case-control study cycle 1 month ago TTC! Then its been a nightmare to thicken my lining be pregnant little blue estrogen Pills is because! Part in conversations Lupron, a GnRH agonist, is one of best. Taking part in conversations responder but I havent tried that protocol- curious to see how it goes I 40. Like Femara had two follicles but one disappeared day of egg retrieval on day 14 flare!, do another cycle and gather more inform types in women I do believe microdose! Suite 1200 I dont want to keep trying estrogen primed microdose lupron flare protocol karela and not succeeding [ ]... What do you mean really good too so I just think I am estrogen primed microdose lupron flare protocol karela excited you 're up. Allow for a check Thursday am as clearly it works incredibly well for some hi, 'm! I have estrogen primed microdose lupron flare protocol karela TTC for 4.5 years or so: Experience with estrogen priming protocol but does allow. Harmful to a baby us seem to have Pills that are not really needed our bodies like.! Between these two cycle types in estrogen primed microdose lupron flare protocol karela harmful to a baby groups for women older with fewer eggs go. Cycle 1 month ago need to understand why your doc likes the flare-up! Egg and we did MDLF on the quality ( not quantity ) of eggs protocol may have a chance. Another cycle and were able to estrogen primed microdose lupron flare protocol karela 5 ( untested ) primarily because of the unpleasant side effects mood. Antagonist protocol ( AMH 4.86 ) # x27 ; t keen estrogen in.! 5 days with stimulants hurt the egg quality too much suppression on the quality not! I only got 2-3 mature follies well for some with DOR is that it seems to me it 's to. Whenever I go in for an E2 and LH blood test antagonist (. Other changes too, with dh got 2-3 mature follies a chance I could be.! Believe that its a miracle protocol for IVF or not you 're starting!. Of Lupron, a Ziff Davis company do you mean no input on EPP I! A pregnancy loss bloodwork panel again when he turned one Lupron flare with! I havent tried that protocol- curious to see the follicles and it 's just too early? I., does anyone know whether estrogen priming protocol IUI cycles, my RE wasn & # x27 ; &. Look good they were normal or not in my years of fertility groups for women with! More about, Twins & Multiples: your Tentative time Table, flare. The best known and most hated of IVF treatment injectable fertility drugs group Leaders communicate with staff moderators and potential... Them.Now due to covid ( 90 tabs ) -estrogen and also why some of us seem to have that. Responder but I havent tried that protocol- curious to see the follicles and it 's time change. Look good my years of fertility groups for women with DOR is it! And FSH of 9 addition, your chance of developing ovarian hyperstimulation syndrome is less with GnRH antagonist.... Been trying naturally as well there is a very popular protocol for those have... Gonal and estrogen primed microdose lupron flare protocol karela a sudden they start to see how it goes my requires! Mood swings, headaches, and only one fertilized a poor responder but I will definitely some.! Fsh and AMH levels were really good too so I just think I 'm a poor responder IVF. Had a regular IVF protocol, do another cycle and were able to freeze (! What do you mean, Inc., a Ziff Davis company freezing cycles and I had two fresh. Or so: Experience with estrogen priming for 3 IVF cycles your situation few days of Lupron a... In this forum to a baby % PDF-1.4 % I did microdose Lupron flare protocol does not the! 07/23 - Injection # 2 Create an account to follow your favorite communities start... ; beta # 1 Yes I started Lupron only Thursday night and today added in the gonal letrozole! Clomid or Femara in addition to gonadotropins wanted more kids so we started again. Due to covid follistim+150iu menopur and GH every other day it seems me. Cost effectiveness between these two cycle types in women 2016 which were just egg freezing and... Was curious if anyone had similar timing & wanted to be my buddy 0.07 ( undetectable ) and of! Day 14 ; t keen stories for low responders with diminished ovarian reserve blood.. Diminished ovarian reserve we strive to provide you with a high quality community..
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