How to use In this way, variability in individuals' pain response was tried to be controlled and will be discussed in part 2 of this manuscript. Provided by the Springer Nature SharedIt content-sharing initiative. Colgate Sensitive Instant Relief Enamel Toothpaste with Pro-Argin technology to help seal and repair the sensitive areas of teeth. The clinical significance of this study can be highlighted by the fact that this was a person-centred clinical trial where patients were the prime focus where thepatients suffering from DH. The impact of FCPS, Pro-argin, and strontium acetate-based treatments of DH on the oral health-related quality of life together with the difference in the effectiveness of treatments were assessed individually rather than in groups in the current six-week trial. Manage cookies/Do not sell my data we use in the preference centre. These findings were similar to a previous study conducted by Schiff et al. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. J Dent. J Oral Sci. In comparison, the Pro-argin can make mechanical barrier of calcium phosphate precipitates on exposed dentinal tubules up to 2m depth by the interaction of positively charged arginine, amino acids and type 1 collagen fibres [8]. Plus it has the freshness you trust from Colgate! Colgate Sensitive Pro-relief Instant Relief. The treatment difference between Pro-argin and 8% strontium acetate was not statistically significant with a p>0.05 for immediate and sustained pain relief in DH and statistically significant relative to control on all clinical parameters of the SCASS and VAS. The total sample size was 140 participants, with thirty-five in each group. Klubpris: 25,46 kr. SCASS and VAS were introduced on each visit as primary and secondary outcome measures, respectively. Dentin hypersensitivity is characterized by a short, sharp pain arising from open dentin tubules in exposed dentin in response to external stimuli, which cannot be attributed to any other defect or disease. Lasting relief with 2x daily continued brushing. BMC Oral Health 21, 498 (2021). There was a significant (p<0.001) reduction of 45.7% with Pro-argin, 37.6% with 8% strontium acetate, 18.1% with FCPS, and 15.2% with NaF-based dentifrices relative to baseline on SCASS after one-minute application on sensitive teeth. 2018. Colgate Sensitive PRO-Relief provides you relief from sudden shocks of pain and long-term sensitivity with regular use. The second null hypothesis was that mean scores for pain due to DH among different treatment groups for sustained relief remains the same, and it was considered to be rejected at a p value0.05. Individuals either with dental caries, heavily restored, or cracked teeth, or with orthodontic or prosthetic appliances, or with localised or generalised gingivitis or pulpitis and heavy calculus or using any desensitising toothpaste or mouth wash or any other desensitising products up to six weeks before the study were excluded from this trial. Hu et al. 0. It has stannous fluoride as an active ingredient. compared Colgate Sensitive Pro Relief to another leading brand that desensitizes with a 2% potassium ion formula. Pro-Argin technology is occlusive. Google Scholar. COLGATE. Venkataramana S, Jeyaraman SK, Kothimbakkam SSK, Chellathurai BNK. There was no statistically significant treatment difference between the two (p=0.499). YYYY Colgate-Palmolive Company. The widely accepted hydrodynamic theory proposes that stimuli can alter the behavior of fluid in the dentin tubules, activating intra-dental nerve fibers and causing pain. Grnberg C, Bauer F, Crispin A, Jakob M, Hickel R, Draenert ME. It contains clinically proven Pro-Argin technology which provides instant and lasting sensitivity relief. 2013;41:S317. Another study by Hines et al. Instant relief when applied directly to the sensitive tooth with the fingertip and gently massaged for 1 minute. Amsterdam: Elsevier; 2015. p. 4576. This site is intended for healthcare professionals only. fluorides, arginine, strontium, and bioactive glasses (BAG) [4] and in-office application of bioactive formulations such as glutaraldehyde, resin-based bonding agents and restorative materials, amorphous calcium phosphate based-tooth mousse, and lasers in the dental clinics [5]. We provided oral hygiene instructions and ways of relieving their pain from DH to improve their quality of life. 3Intervention for Group C denotes Sensodyne Rapid Action. Douglas-de-Oliveira DW, Vitor GP, Silveira JO, Martins CC, Costa FO, Cota LOM. I am interested to hear you guys opinion and thought about it. Department of Oral Biology, Dr. Ishrat-Ul-Ebad Khan Institute of Oral Health Sciences (DIKIOHS), Dow University of Health Sciences, Karachi, Pakistan, Department of Oral Biology, Dow Dental College, Dow University of Health Sciences, Karachi, Pakistan, Department of Research, School of Public Health, Dow University of Health Sciences, Karachi, Pakistan, You can also search for this author in Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. (US). If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. The strength of this study was that participants were randomised into four treatment groups to generalise the results for the population [32]. Thus, 128 participants completed the trial and were statistically analyzed for primary outcome measure of SCASS scores after lost to follow up (Fig. In addition, they should be reproducible and clinically relevant to stimuli triggering pain in DH [35]. Colgate Professional has resources to help your patients understand what causes enamel erosion and how to avoid falling into those traps. Internal report 2018, 5. Lg i kurv. Elsevier; 2015. p. 3344. 90 sold. Lai HY, Lee S, Toh SW, Li Y, Mateo LR, Morrion BM, Zhang Y: The clinical efficacy of a new dentifrice with zinc on plaque and gingivitis. 1). DH most commonly involves the facial surfaces of maxillary and mandibular permanent teeth. Panagakos F, Schiff T, Guignon A. Dentin hypersensitivity: effective treatment with an in-office desensitizing paste containing 8% arginine and calcium carbonate. Docimo R, Montesani L, Maturo P, Costacurta M, Bartolino M, DeVizio W, Zhang YP, Cummins D, Dibart S, Mateo LR: Comparing the Efficacy in Reducing Dentine Hypersensitivity of a New Toothpaste Containing 8.0% Arginine, Calcium Carbonate, and 1450 ppm Fluoride to a Commercial Sensitive Toothpaste Containing 2% Potassium Ion: An Eight-Week Clinical Study in Rome, Italy. This site is intended for healthcare professionals only. Last updated on May 11, 2021. https://clinicaltrials.gov/ct2/show/NCT04249336. Colgate Sensitive Pro-Relief toothpaste is a revolutionary and one-of-its kind remedy that can provide consumers suffering from Sensitivity the much needed instant and long lasting relief . Frequency of dentin hypersensitivity: a cross-sectional study. Colgate Sensitive Pro Relief offers a solution that is clinically proven to relieve sensitivity pain. Most sensitive toothpastes primarily numb the discomfort, whereas Colgate Sensitive Pro-Relief works to relieve sensitivity by plugging the channels that lead to sensitive tooth nerves. Tel: +381 (0)21 452-910, +381 (0)21 420-758. 2019;88:103170. J Evid Based Dent Pract. In addition, participants were asked to record the overall sensitivity of their day-to-day experience on provided VAS sheets reporting pain on brushing, taking hot or cold beverages, and rinsing with tap water for the six weeks of the study. The sensitive toothpaste remineralises tooth enamel for more resistance against acid attacks. For more great Dental Care products like toothpaste and mouthwash, continue browsing online and buy in-store at B&M. Colgate Sensitive Instant Relief Toothpaste 75ml Product code: 326795 2.49 Subject to availability - visit your nearest store All participants were instructed to dry the tooth surface with the cotton ball and apply a paste of about half-inch length on the dried surface for one minute, then brush the teeth twice daily after breakfast and before sleep as per directions demonstratedon the study model. Two double-blind randomized clinical studies by Nathoo et al. Book With its unique Pro-Argin technology, this sensitive toothpaste will give you instant* relief from sensitivity as it helps to seal and repair the sensitive areas of your teeth. Article The loss of tooth enamel is the most common cause of tooth sensitivity and is not affected by cavities, gum disease, or other problems. Pro-argin resulted in the immediate treatment response and statistically significant (p<0.001) clinical reduction in DH than FCPS in the present study, as shown in Table 3. The probable reason for variations between this clinical trial and previously conducted studies could be attributed to racial or ethnic differences between the conducted trials. Trials. For instant relief, apply directly to each sensitive tooth surface and massage for one minute, up to twice a day. Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. It is clinically proven for instant and lasting Sensitivity relief* How does it work? Dentine hypersensitivity. J Clin Periodontol. Product Information. J Clin Dent. Part of Buy Colgate Sensitive Pro Relief and get the best deals at the lowest prices on eBay! YES Somewhat No Martins C, Firmino R, Riva J, Ge L, Carrasco-Labra A, Brignardello-Petersen R, et al. For instant relief, just apply directly to the sensitive tooth with fingertip and gently massage for one minute. Follow the directions for use. CONSORT flow chart. 2010;23(Spec No A):14A-9A. The sealed envelope contained details of unique subject numbers assigned individually in ascending order, group titles, and treatment codes and was placed in the box. Based on the outcomes of previous systematic reviews and meta-analysis, the rationale of the present study was to substantiate the claim of immediate pain relief after one-minute application in DH by non-invasive surface application of OTC dentifrices containing Pro-arginin Colgate Sensitive Pro-Relief, and 8% strontium acetate in Sensodyne Rapid Action and other objective was the comparative evaluation of the clinical efficacy of three technologies, BAG-based FCPS in BioMinR F, Pro-argin, and 8% strontium acetate at efficacy intervals of day three, week two, four and six for sustained inhibition of painful stimulus provoking DH as all three are dentinal tubular occluding dentifrices. In addition, they were responding to air-blast stimulus on the Schiff cold air sensitivity scale (SCASS) with scores2 [22]. Pessoa OF, Loretto SC, Maia LC. Baseline scores were recorded to measure the intensity of pain due to DH on SCASS with scores2 [22] against air blast stimulus with a triple syringe of the dental unit and on a linear VAS of 10cm length with scores4cm [23], against mechanical stimulus with a dental probe and water jet stimulus with a triple syringe. We discuss how this innovative technology works to provide patients with rapid and long-lasting relief from dentin hypersensitivity. 2017;457:2530. 2019;81:16. YYYY Colgate-Palmolive Company. Wilcoxon Signed-Rank Test was used to compute mean scores relative to baseline at each time point. 4.2 5 0 221 221 Colgate Sensitive Pro-Relief Enamel Rebuild toothpaste helps instantly repair sensitive teeth and provides lasting protection against hypersensitivity. If symptoms persist, talk to your healthcare professional. Find products and services. Mason S, Hughes N, Sufi F, Bannon L, Maggio B, North M, et al. *with direct application and daily brushing. J Dent Probl Solut. Colgate Sensitive Pro-Relief Enamel Repair contains Pro-Argin formula, helping to remineralise enamel, strengthen teeth against acid in food and drinks, plus instantly plugs channels to sensitive nerves. Matranga D, Matera F, Pizzo G. Evaluating the statistical methodology of randomized trials on dentin hypersensitivity management. Colgate-Palmolive Company 2018. Effect of dentin hypersensitivity treatment on oral health related quality of lifea systematic review and meta-analysis. Pro-Argin technology can be found in Colgate Sensitive Pro Relief Toothpaste, sold as Colgate Sensitive Instant Relief in the UK and elmex Sensitive Professional in Europe. Follow the directions for use. J Clin Dent. * For instant relief, apply directly to the sensitive tooth with finger tip and gently massage for 1 minute. 2020;99(5):51422. [41] was performed in 2017 and reported inappropriate statistical methodologies related to the normal distribution of data and equality of variances, along with lacking information in 77.1% of the thirty-five randomised trials on DH management. p values of<0.05 were considered as statistically significant. Can be used after the Colgate Sensitive Pro-Relief Desensitizing Paste. West N, Newcombe RG, Hughes N, Mason S, Maggio B, Sufi F, et al. Springer Nature. [10] examined the evidence for strontium acetate and Pro-argin in 2018, and their findings depicted low quality of evidence for strontium acetate on the Grading of Recommendations, Assessment, Development, and Evaluations system (GRADE). If the enamel is too thin, has tiny tubules that reveal the underlying dentin, or is worn down in some places. Cookies policy. Listing a study does not mean it has been evaluated by the U.S. Federal Government. A total of 140 met the eligibility criteria with at least two sensitive teeth anterior to molars due to erosions or abrasions with or without an associated gingival recession. Providing effective solutions for this prevalent condition is a priority for every dental professional, and Colgates Pro-Argin technology is helping dentists lead the way. The outcomes are in concordance with the previous studies conducted by Layer and Hughes [26], Zang and Shaw [27], and Mason et al. Click here. CONCLUSION: The study results support the following conclusions: (1) Colgate Sensitive Pro-Relief toothpaste provides a significantly more reduction in dentin hypersensitivity than Sensodyne. It revealed an immediate improvement with strontium acetate more than Pro-argin on SCASS. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste is an everyday toothpaste. 2009; 20 (Spec Iss): 1722. ^Vs novamin/sodium fluoride technology and stannous fluoride/sodium fluoride technology (p<0.05). Shrimathi S. Effect of BiominF, NovaminR, Argin and nanohydroxy particles containing dentifrices on dentine hypersensitivity and gingivitis among 3544 years aged population of Madurai district: a randomized controlled trial (RCT). Table 4 demonstrates a comparison between treatment groups observing better clinical efficacy in managing DH on SCASS. Size: 75ml (Approx.) 2019;40(10):6537 (quiz 8). Colgate Sensitive Pro Relief can be applied directly to the affected area for almost instant relief. Dentin hypersensitivity (DH) is a sharp toothache that influences a patients' oral health-related quality of life. A 3-day randomised clinical study investigating the efficacy of two toothpastes, designed to occlude dentine tubules, for the treatment of dentine hypersensitivity. [22] reporting the instant relief from DH by 44.1% with Pro-argin on SCASS. Effectiveness of dentifrices with new formulations for the treatment of dentin hypersensitivitya meta-analysis. In addition, patients were educated regarding the cause of the disease for prevention and awareness of oral hygiene measures, brushing techniques, and dietary influences in DH. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. Post-application changes on SCASS were observed after one minute, three days, two, four, and six weeks, subsequently. Written consent was obtained from all participants to participate in the six-week clinical trial. This clinical trial was not funded by any agency in public, commercial or not-for-profit sectors. Not all desensitizing toothpastes perform equally well. 1. Register now and gain access to: 8 hours ECPD Product samples Patient materials Register here * For instant relief, apply directly to the sensitive tooth with finger tip and gently massage for 1 minute. Am J Dent. Colgate SENSITIVE PRO-Relief has been rebranded to Colgate SENSITIVE INSTANT Relief . 2017;59(4):4618. *Fr omedelbar lindring ska du applicera direkt p den knsliga . The findings agreed with another in vitro trial by Mahmoodi et al. Identifier NCT 04249336. Kp nu. 1997;24(11):80813. who examined FCPS and Pro-argin formulations in 2018. statement and Friedman Test was used to observe post-application change in treatment responses within the group for 6weeks. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. PubMedGoogle Scholar. Researchers have investigated the clinical efficacy of popular propriety occluding dentifrices containing Pro-argin, strontium acetate, and FCPS formulations for treating DH and have found no adverse effects. How does Colgate Sensitive Pro-Relief Repair & Prevent work? Lasting protection with regular use. There is no problem with every day and prolonged use. Use regularly to enjoy long-lasting relief from sensitivity*. A randomised, controlled, triple-blinded clinical trial was conducted with 140 participants clinically diagnosed with DH and equally randomized into four groups with parallel treatment assignment of FCPS, Pro-Argin, 8% strontium acetate, and sodium fluoride-based OTC dentifrices, and tested for DH with air blast, mechanical, and water jet stimuli on SCHIFF cold air sensitivity scale (SCASS) and visual analogue scale (VAS) at interim efficacy intervals of one minute, three days, two, four, and six weeks, subsequently. Gillam D, Hill R, Samueli A. Bioactive glasses in the management of dentine hypersensitivity: a review. Work with Colgate Professional to help provide better oral care to your patients. More robust trials with a large number of participants are recommended for furtherassessing the impact of DH on the oral health-related quality of life and the difference in the effectiveness of treatments. Grading of Recommendations, Assessment, Development and Evaluations. Was this answer helpful? Poster #0742, March 2018 AADR. The prevalence of DH was found to vary from about 5 to 62% owing to the use of different diagnostic and measuring tools and age groups in the published literature, with the best average estimate of 34% worldwide [3]. While FCPS in BioMin F can be the best possible treatment option for long-term management of DH in the form of OTC dentifrices. Free postage. blokerer jeblikkeligt smerter fra isninger. A randomised clinical trial on the efficacy of 5% fluorocalcium phosphosilicate-containing novel bioactive glass toothpaste. Treatments provided to the patients were OTC dentifrices marketed with the claim of immediate pain relief in DH. 1). The secondary objective of the study was to compare the clinical efficacy of Pro-argin, strontium acetate, and FCPS for immediate and sustained treatment response in DH that was measured on SCASS as a primary outcome measure and VAS as secondary outcome measure at efficacy intervals of one minute, day-three, week two, four and six. Colgate Sensitive Instant* Relief Enamel Repair Toothpaste gives you clinically proven lasting relief** from sensitivity for 8 weeks when you use it twice a day. The statistician was also kept blinded. Clinically proven Instant and lasting Sensitivity relief*. Dentinal tubules occluded by bioactive glass-containing toothpaste exhibit high resistance toward acidic soft drink challenge. Today's era of flourishing research in DH is based on incorporating bioactive ingredients in commercially available oral dentifrices that can induce deep intratubular remineralisation of dental hard tissues for permanent or long-term treatment purposes. Participants were recalled at interim efficacy intervals of three days, two weeks, four weeks, and six weeks for assessment of sustained relief. 2019;46(12):11216. Width 17 Height 5 Depth 3.8 Show More Payment & Refunds Directions *For instant relief, apply directly to the sensitive tooth with fingertip, and massage gently for 60 seconds, one a week or less frequently **For lasting relief, apply to a gentle toothbrush making sure to brush all sensitive areas of the teeth.
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